Zyprexa and Robinul drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyprexa (olanzapine) and Robinul (glycopyrrolate). Common drug interactions include device failure among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Robinul. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.



On Jul, 15, 2026

26 people who take Zyprexa and Robinul together, and have interactions are studied.

Zyprexa and Robinul drug interactions.

What are the common drug interactions of Zyprexa and Robinul, by gender? *:

female:

  1. Device failure
  2. Drug toxicity
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Pain in extremity
  5. Urinary tract infection
  6. Abasia (inability to walk)
  7. Abdominal distension
  8. Abdominal pain
  9. Abdominal pain upper
  10. Adrenal mass

male:

  1. Anaemia (lack of blood)
  2. Platelet count decreased
  3. Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
  4. Nausea (feeling of having an urge to vomit)
  5. Plasma cell myeloma (cancer that begins in plasma cells)
  6. Pulmonary haemorrhage (acute bleeding from the lung)
  7. Respiratory tract infection
  8. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  9. Urinary tract infection
  10. Venous thrombosis limb (blood clot that forms in a vein in the limb)

What are the common drug interactions of Zyprexa and Robinul, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abnormal behaviour
  2. Aggression
  3. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  4. Pulmonary haemorrhage (acute bleeding from the lung)

20-29:

  1. Obesity (having too much body fat)
  2. Type 2 diabetes mellitus

30-39:

  1. Blood testosterone decreased
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Feeling hot
  4. Gallbladder disorder
  5. Gastrointestinal motility disorder (abnormal intestinal contractions)
  6. Serum serotonin decreased

40-49:

  1. Device failure
  2. Drug toxicity
  3. Plasma cell myeloma (cancer that begins in plasma cells)

50-59:

  1. Abdominal distension
  2. Abdominal pain
  3. Abdominal pain upper
  4. Adrenal mass
  5. Agitation (state of anxiety or nervous excitement)
  6. Back pain
  7. Chest pain
  8. Deafness unilateral
  9. Dementia (madness)
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

60+:

  1. Anaemia (lack of blood)
  2. White blood cell count decreased
  3. Unevaluable reaction
  4. Urinary tract infection
  5. Platelet count decreased
  6. Asthenia (weakness)
  7. Confusional state
  8. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  9. Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
  10. Failure to thrive (inadequate weight gain and physical growth in children)

What are the existing conditions these people have? *

  1. Pain: 6 people, 23.08%
  2. Nausea And Vomiting: 4 people, 15.38%
  3. Nausea (feeling of having an urge to vomit): 4 people, 15.38%
  4. Mesothelioma (rare type of cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium): 3 people, 11.54%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 7.69%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 7.69%
  7. Multiple Myeloma (cancer of the plasma cells): 2 people, 7.69%
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Zyprexa and Robinul?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Zyprexa and Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyprexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robinul and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on olanzapine and glycopyrrolate (the active ingredients of Zyprexa and Robinul, respectively), and Zyprexa and Robinul (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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