Zyprexa and Thiothixene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyprexa (olanzapine) and Thiothixene (thiothixene). Common drug interactions include overdose among females and weight increased among males.

The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Thiothixene. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

What is Thiothixene?

Thiothixene has active ingredients of thiothixene. eHealthMe is studying from 321 Thiothixene users. Check the latest studies of Thiothixene.

On Jul, 14, 2026

51 people who take Zyprexa and Thiothixene together, and have interactions are studied.

Zyprexa and Thiothixene drug interactions.

What are the common drug interactions of Zyprexa and Thiothixene, by gender? *:

female:

Overdose
Sedation
Hyperglycaemia (high blood sugar)
Increased appetite
Diabetic eye disease
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hyperinsulinaemia (excess levels of insulin circulating in the blood)
Insulin resistance
Oedema peripheral (superficial swelling)
Urinary incontinence (inability to control the flow of urine and involuntary urination)

male:

Weight increased
Blood glucose increased
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematuria (presence of blood in urine)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Malaise (a feeling of general discomfort or uneasiness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Abdominal pain
Arthralgia (joint pain)

What are the common drug interactions of Zyprexa and Thiothixene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Agitation (state of anxiety or nervous excitement)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Sedation
Aggression
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anger
Dyskinesia (abnormality or impairment of voluntary movement)
Impulse-control disorder
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Suicidal ideation

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Diabetes mellitus inadequate control
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Malaise (a feeling of general discomfort or uneasiness)
Arthralgia (joint pain)
Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
Blood glucose increased

40-49:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Injection site discomfort
Injection site haematoma (localized swelling filled with blood at injection site)
Ketoacidosis (high concentrations of ketone bodies in blood)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nervousness
Nocturia (the need to get up in the night to urinate)
Oedema peripheral (superficial swelling)
Polyuria (production of too much dilute urine)
Presbyopia (a condition in which the lens of the eye loses its ability to focus, making it difficult to see objects up close)

50-59:

Obesity (having too much body fat)
Weight increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hypertension (high blood pressure)
Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
Tardive dyskinesia (a disorder that involves involuntary movements)
Type 2 diabetes mellitus
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood cholesterol increased

60+:

Blood creatine phosphokinase increased
Blood glucose increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Haematocrit decreased
Haemoglobin decreased
Hallucination (an experience involving the perception of something not present)
Incontinence (lack of moderation or self-control)
Lethargy (tiredness)
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 10 people, 19.61%
Psychotic Disorder: 5 people, 9.80%
Depression: 5 people, 9.80%
Stress And Anxiety: 4 people, 7.84%
Insomnia (sleeplessness): 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

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