Zyvox and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyvox (linezolid) and Fentanyl citrate (fentanyl citrate). Common drug interactions include acquired porphyria among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Zyvox and Fentanyl citrate. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

On Jul, 30, 2026

30 people who take Zyvox and Fentanyl citrate together, and have interactions are studied.

Zyvox and Fentanyl citrate drug interactions.

What are the common drug interactions of Zyvox and Fentanyl Citrate, by gender? *:

female:

Acquired porphyria (group of disorders that result in a build up of chemicals called porphyrins in the body)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Asthma
Back pain
Bacteraemia (presence of bacteria in the blood)
Blood glucose increased
Blood urea increased
Bone disorder

male:

Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal wall cyst (abnormal membranous sac containing a gaseous, liquid, or semisolid substance on abdominal wall)
Altered state of consciousness (altered state of mind)
Anal erosion
Anal polyp (abnormal growth sticking out from the mucous membrane lining the anus or colon)
Bacteraemia (presence of bacteria in the blood)
Burkholderia test positive

What are the common drug interactions of Zyvox and Fentanyl Citrate, by age (0-1 to 60+)? *:

0-1:

Anaemia (lack of blood)
Catheter site erythema (redness of skin at catheter site)
Chylothorax (collection of lymph fluid around the lung)
Diarrhoea
Erythema (redness of the skin)
Hypokalaemia (low potassium)
Mediastinitis (inflammation of the tissues in the mid-chest)
Pericardial effusion (fluid around the heart)
Rash
Rhinorrhoea (watery mucus discharge from the nose)

2-9:

n/a

10-19:

Hypoproteinaemia (too little prolactin circulating in the blood)

20-29:

n/a

30-39:

Abnormal faeces (abnormal stool)
Blood urea increased
Cardiac tamponade (fluid accumulates in heart covering)
Coagulopathy (blood's ability to clot is impaired)
Faeces discoloured
Fasciitis (infection of muscle surrounding tissue)
Hyperglycaemia (high blood sugar)
Neoplasm progression (growth of tumour)
Pericarditis (inflammation of the pericardium)
Pleural effusion (water on the lungs)

40-49:

Hypertension (high blood pressure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abscess limb (limb infection)
Anal abscess
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
Emotional distress
Gangrene (body tissue dies)
Gastrointestinal stoma complication (complication of an opening surgically made in digestive tract)

50-59:

Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
Heparin-induced thrombocytopenia
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Pneumonia
Respiratory distress (difficulty in breathing)
Thrombocytopenia (decrease of platelets in blood)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)

60+:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Acquired porphyria (group of disorders that result in a build up of chemicals called porphyrins in the body)
Bone fragmentation
Breast cancer recurrent
Caecitis (inflammation of the cecum)
Candidiasis (candidiasis or thrush is a fungal infection)
Cardiogenic shock (inadequate circulation of blood)
Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue)
Cholangitis chronic (long lasting infection of the bile duct)
Cholecystitis acute (rapid infection of gallbladder)

What are the existing conditions these people have? *

Staphylococcal Infection (an infection with staphylococcus bacteria): 5 people, 16.67%
Infection: 3 people, 10.00%
Hypotension (abnormally low blood pressure): 3 people, 10.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 6.67%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%
Iron Overload: 2 people, 6.67%
Ill-Defined Disorder: 2 people, 6.67%
Constipation: 2 people, 6.67%
Cancer Pain: 2 people, 6.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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