Zyvox and Fungizone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zyvox (linezolid) and Fungizone (amphotericin b). Common drug interactions include leukoencephalopathy among females and septic shock among males.
The phase IV clinical study analyzes what interactions people have when they take Zyvox and Fungizone. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Zyvox?
Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.
What is Fungizone?
Fungizone has active ingredients of amphotericin b. eHealthMe is studying from 4,456 Fungizone users. Check the latest studies of Fungizone.
20 people who take Zyvox and Fungizone together, and have interactions are studied.

What are the common drug interactions of Zyvox and Fungizone, by gender? *:
female:
- Leukoencephalopathy (disease of the white matter in the brain)
- Acute respiratory failure
- Contusion (a type of hematoma of tissue in which capillaries)
- Death
- Fall
- Head injury
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
- Septic shock (shock due to blood infection)
- White blood cell count increased
male:
- Septic shock (shock due to blood infection)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Malaise (a feeling of general discomfort or uneasiness)
- Multi-organ failure (multisystem organ failure)
- Nausea (feeling of having an urge to vomit)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Platelet count decreased
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
- Pyelonephritis (inflammation of kidney caused by bacteria)
What are the common drug interactions of Zyvox and Fungizone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
- White blood cell count increased
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Pyrexia (fever)
- Dysgeusia (disorder of the sense of taste)
- Hair colour changes
- Hypertension (high blood pressure)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Platelet count decreased
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
50-59:
n/a
60+:
- Septic shock (shock due to blood infection)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Bladder discomfort
- Blood bilirubin increased
- Blood creatinine increased
- Contusion (a type of hematoma of tissue in which capillaries)
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Fall
- Fungal sepsis (whole body infection by fungus)
- Gamma-glutamyltransferase increased
What are the existing conditions these people have? *
- Septic Shock (shock due to blood infection): 3 people, 15.00%
- Scedosporium Infection (a filamentous fungus which occasionally causes infections in humans): 3 people, 15.00%
- Respiratory Disorder (respiratory disease): 3 people, 15.00%
- Pneumonia: 3 people, 15.00%
- Neuralgia (pain in one or more nerves): 3 people, 15.00%
- Liposarcoma (a cancer tumour that arises in fat cells in deep soft tissue): 3 people, 15.00%
- Cachexia (loss of weight): 3 people, 15.00%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 15.00%
- Sedation: 2 people, 10.00%
- Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zyvox and Fungizone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zyvox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fungizone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zyvox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fungizone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on linezolid and amphotericin b (the active ingredients of Zyvox and Fungizone, respectively), and Zyvox and Fungizone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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