Zyvox and Lidoderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyvox (linezolid) and Lidoderm (lidocaine). Common drug interactions include nasal congestion among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Zyvox and Lidoderm. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

On Aug, 04, 2026

52 people who take Zyvox and Lidoderm together, and have interactions are studied.

What are the common drug interactions of Zyvox and Lidoderm, by gender? *:

female:

Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Scab (a hard coating on the skin formed during the wound healing)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Hyperglycaemia (high blood sugar)
Foot deformity (functional disability of foot)
Osteonecrosis (death of bone)
Otitis externa (external ear infection)
Nausea (feeling of having an urge to vomit)

male:

Anaemia (lack of blood)
Body temperature increased
Leukocytosis (increased white blood cells)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphatic obstruction (blockage in lymphatic duct)
Pleural effusion (water on the lungs)
Renal failure (kidney dysfunction)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)

What are the common drug interactions of Zyvox and Lidoderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Brain injury
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Lacunar infarction (a type of stroke)
Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

n/a

50-59:

Lung disorder (lung disease)
Malocclusion (a misalignment)
Metastatic neoplasm (spreadable cancer tumour)
Mouth ulceration (mouth ulcers)
Oedema peripheral (superficial swelling)
Oliguria (not enough urine)
Osteitis deformans (a disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain)
Osteolysis (dissolution of bone)
Osteomyelitis (infection of bone)
Osteopenia (a condition where bone mineral density is lower than normal)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Metastases to spine (cancer spreads to spine)
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Pain in jaw
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
Spinal decompression (relief of pressure on one or many pinched nerves (neural impingement) of the spinal column)
Urinary tract infection

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 27 people, 51.92%
Osteoporosis (bones weak and more likely to break): 27 people, 51.92%
Thrombocytopenia (decrease of platelets in blood): 11 people, 21.15%
Neoplasm Malignant (cancer tumour): 11 people, 21.15%
Nausea (feeling of having an urge to vomit): 3 people, 5.77%
Infection: 3 people, 5.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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