Zyvox and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zyvox (linezolid) and Premarin (estrogens, conjugated). Common drug interactions include anhedonia among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Zyvox and Premarin. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Zyvox?

Zyvox has active ingredients of linezolid. It is often used in mrsa infection. eHealthMe is studying from 9,399 Zyvox users. Check the latest studies of Zyvox.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Aug, 08, 2026

51 people who take Zyvox and Premarin together, and have interactions are studied.

What are the common drug interactions of Zyvox and Premarin, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Disability
Injury
Pain in jaw
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Spinal osteoarthritis (joint cartilage loss in spine)
Depression
Renal cyst (kidney cyst)
Leukopenia (less number of white blood cells in blood)

male:

Agitation (state of anxiety or nervous excitement)
Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anisocytosis (patient's red blood cells are of unequal size)
Anxiety
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Asthma
Bacteraemia (presence of bacteria in the blood)
Balance disorder
Blood glucose increased

What are the common drug interactions of Zyvox and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Nausea (feeling of having an urge to vomit)

50-59:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Arthralgia (joint pain)
Asthma
Back pain
Bacteraemia (presence of bacteria in the blood)
Blood creatinine increased
Blood glucose increased
Bone fragmentation
Bone marrow granuloma (collection of inflammatory cells in bone marrow)
Bone pain

60+:

Fall
Anxiety
Pain in jaw
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Spinal osteoarthritis (joint cartilage loss in spine)
Depression
Renal cyst (kidney cyst)
Leukopenia (less number of white blood cells in blood)
Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
Toothache (tooth pain)

What are the existing conditions these people have? *

Staphylococcal Infection (an infection with staphylococcus bacteria): 6 people, 11.76%
Migraine (headache): 4 people, 7.84%
Osteoporosis (bones weak and more likely to break): 3 people, 5.88%
Nausea (feeling of having an urge to vomit): 3 people, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.88%
Diabetes: 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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