A study for a 59 year old man who takes Atorvastatin Calcium, Terazosin Hydrochloride, Vyvanse, Asa, Pregabalin, Venlafaxine Hydrochloride, Lorazepam (an AI-powered real world drug study)

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Number of reports submitted per year:

Information of the patient in this study:

• Age: 59
• Gender: male
• Conditions: Type Iv Lipidaemia, Hypertension, Peripheral Vascular Disease, Major Depression, Anxiety Disorder
• Drugs taken:
  • Atorvastatin Calcium (atorvastatin calcium)
  • Terazosin Hydrochloride (terazosin hydrochloride)
  • Vyvanse (lisdexamfetamine dimesylate)
  • Asa (aspirin)
  • Pregabalin (pregabalin)
  • Venlafaxine Hydrochloride (venlafaxine hydrochloride)
  • Lorazepam (lorazepam)

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Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

• Fatigue Aggravated (feeling of tiredness):
  - among males aged 59 (±5) who take the same drugs: 0% (0 of 17)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 2)
• Muscle Spasm:
  - among males aged 59 (±5) who take the same drugs: 0% (0 of 17)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 2)
• Muscle Fatigue (a condition in which muscles cannot exert their normal force):
  - among males aged 59 (±5) who take the same drugs: 0% (0 of 17)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 2)
• Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up):
  - among males aged 59 (±5) who take the same drugs: 0% (0 of 17)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 2)

By each condition:

• people who have Fatigue Aggravated with Type Iv Lipidaemia:
  - among males aged 59 (±5) who have Type Iv Lipidaemia: 0% (0 of 0)
  - among people who have Type Iv Lipidaemia, regardless of gender or age: 0% (0 of 0)
• people who have Fatigue Aggravated with Hypertension:
  - among males aged 59 (±5) who have Hypertension: 4.61% (2,557 of 55,473)
  - among people who have Hypertension, regardless of gender or age: 5.05% (30,739 of 608,860)
• people who have Fatigue Aggravated with Peripheral Vascular Disease:
  - among males aged 59 (±5) who have Peripheral Vascular Disease: 0% (0 of 32)
  - among people who have Peripheral Vascular Disease, regardless of gender or age: 0% (0 of 484)
• people who have Fatigue Aggravated with Major Depression:
  - among males aged 59 (±5) who have Major Depression: 4.15% (57 of 1,374)
  - among people who have Major Depression, regardless of gender or age: 3.52% (1,119 of 31,832)
• people who have Fatigue Aggravated with Anxiety Disorder:
  - among males aged 59 (±5) who have Anxiety Disorder: 5.46% (36 of 659)
  - among people who have Anxiety Disorder, regardless of gender or age: 5.69% (777 of 13,648)
• people who have Muscle Fatigue with Major Depression:
  - among males aged 59 (±5) who have Major Depression: 2.55% (35 of 1,374)
  - among people who have Major Depression, regardless of gender or age: 2.34% (745 of 31,832)
• people who have Muscle Fatigue with Peripheral Vascular Disease:
  - among males aged 59 (±5) who have Peripheral Vascular Disease: 3.13% (1 of 32)
  - among people who have Peripheral Vascular Disease, regardless of gender or age: 2.27% (11 of 484)
• people who have Muscle Fatigue with Hypertension:
  - among males aged 59 (±5) who have Hypertension: 3.67% (2,038 of 55,473)
  - among people who have Hypertension, regardless of gender or age: 4.45% (27,087 of 608,860)
• people who have Muscle Fatigue with Anxiety Disorder:
  - among males aged 59 (±5) who have Anxiety Disorder: 2.73% (18 of 659)
  - among people who have Anxiety Disorder, regardless of gender or age: 3.45% (471 of 13,648)
• people who have Muscle Fatigue with Type Iv Lipidaemia:
  - among males aged 59 (±5) who have Type Iv Lipidaemia: 0% (0 of 0)
  - among people who have Type Iv Lipidaemia, regardless of gender or age: 0% (0 of 0)
• people who have Muscle Spasm with Hypertension:
  - among males aged 59 (±5) who have Hypertension: 1.23% (685 of 55,473)
  - among people who have Hypertension, regardless of gender or age: 1.36% (8,269 of 608,860)
• people who have Muscle Spasm with Major Depression:
  - among males aged 59 (±5) who have Major Depression: 0.44% (6 of 1,374)
  - among people who have Major Depression, regardless of gender or age: 0.89% (282 of 31,832)
• people who have Muscle Spasm with Anxiety Disorder:
  - among males aged 59 (±5) who have Anxiety Disorder: 1.67% (11 of 659)
  - among people who have Anxiety Disorder, regardless of gender or age: 1.21% (165 of 13,648)
• people who have Muscle Spasm with Peripheral Vascular Disease:
  - among males aged 59 (±5) who have Peripheral Vascular Disease: 0% (0 of 32)
  - among people who have Peripheral Vascular Disease, regardless of gender or age: 0% (0 of 484)
• people who have Muscle Spasm with Type Iv Lipidaemia:
  - among males aged 59 (±5) who have Type Iv Lipidaemia: 0% (0 of 0)
  - among people who have Type Iv Lipidaemia, regardless of gender or age: 0% (0 of 0)
• people who have Orthostatic Hypotension with Peripheral Vascular Disease:
  - among males aged 59 (±5) who have Peripheral Vascular Disease: 0% (0 of 32)
  - among people who have Peripheral Vascular Disease, regardless of gender or age: 0.21% (1 of 484)
• people who have Orthostatic Hypotension with Type Iv Lipidaemia:
  - among males aged 59 (±5) who have Type Iv Lipidaemia: 0% (0 of 0)
  - among people who have Type Iv Lipidaemia, regardless of gender or age: 0% (0 of 0)
• people who have Orthostatic Hypotension with Major Depression:
  - among males aged 59 (±5) who have Major Depression: 0.66% (9 of 1,374)
  - among people who have Major Depression, regardless of gender or age: 0.39% (123 of 31,832)
• people who have Orthostatic Hypotension with Anxiety Disorder:
  - among males aged 59 (±5) who have Anxiety Disorder: 0.91% (6 of 659)
  - among people who have Anxiety Disorder, regardless of gender or age: 0.32% (43 of 13,648)
• people who have Orthostatic Hypotension with Hypertension:
  - among males aged 59 (±5) who have Hypertension: 0.34% (186 of 55,473)
  - among people who have Hypertension, regardless of gender or age: 0.62% (3,776 of 608,860)

By each drug (FDA data only):

• people who take Atorvastatin Calcium and have Fatigue Aggravated:
  - among males aged 59 (±5) who take Atorvastatin Calcium and have side effects: 6.17% (407 of 6,599)
  - among people who take Atorvastatin Calcium and have side effects, regardless of gender or age: 6.62% (4,814 of 72,761)
• people who take Terazosin Hydrochloride and have Fatigue Aggravated:
  - among males aged 59 (±5) who take Terazosin Hydrochloride and have side effects: 3.7% (9 of 243)
  - among people who take Terazosin Hydrochloride and have side effects, regardless of gender or age: 5.87% (109 of 1,857)
• people who take Lorazepam and have Fatigue Aggravated:
  - among males aged 59 (±5) who take Lorazepam and have side effects: 8.1% (867 of 10,703)
  - among people who take Lorazepam and have side effects, regardless of gender or age: 8.04% (13,009 of 161,735)
• people who take Venlafaxine Hydrochloride and have Fatigue Aggravated:
  - among males aged 59 (±5) who take Venlafaxine Hydrochloride and have side effects: 4.3% (34 of 790)
  - among people who take Venlafaxine Hydrochloride and have side effects, regardless of gender or age: 10.2% (1,574 of 15,425)
• people who take Pregabalin and have Fatigue Aggravated:
  - among males aged 59 (±5) who take Pregabalin and have side effects: 8.94% (484 of 5,416)
  - among people who take Pregabalin and have side effects, regardless of gender or age: 8.75% (6,390 of 73,061)
• people who take Asa and have Fatigue Aggravated:
  - among males aged 59 (±5) who take Asa and have side effects: 7.67% (234 of 3,051)
  - among people who take Asa and have side effects, regardless of gender or age: 8.67% (2,775 of 32,022)
• people who take Vyvanse and have Fatigue Aggravated:
  - among males aged 59 (±5) who take Vyvanse and have side effects: 7.69% (23 of 299)
  - among people who take Vyvanse and have side effects, regardless of gender or age: 6.78% (1,905 of 28,085)
• people who take Venlafaxine Hydrochloride and have Muscle Fatigue:
  - among males aged 59 (±5) who take Venlafaxine Hydrochloride and have side effects: 3.04% (24 of 790)
  - among people who take Venlafaxine Hydrochloride and have side effects, regardless of gender or age: 5.01% (773 of 15,425)
• people who take Pregabalin and have Muscle Fatigue:
  - among males aged 59 (±5) who take Pregabalin and have side effects: 4.93% (267 of 5,416)
  - among people who take Pregabalin and have side effects, regardless of gender or age: 5.4% (3,946 of 73,061)
• people who take Lorazepam and have Muscle Fatigue:
  - among males aged 59 (±5) who take Lorazepam and have side effects: 4.06% (435 of 10,703)
  - among people who take Lorazepam and have side effects, regardless of gender or age: 4.93% (7,972 of 161,735)
• people who take Vyvanse and have Muscle Fatigue:
  - among males aged 59 (±5) who take Vyvanse and have side effects: 2.01% (6 of 299)
  - among people who take Vyvanse and have side effects, regardless of gender or age: 2.3% (645 of 28,085)
• people who take Terazosin Hydrochloride and have Muscle Fatigue:
  - among males aged 59 (±5) who take Terazosin Hydrochloride and have side effects: 7% (17 of 243)
  - among people who take Terazosin Hydrochloride and have side effects, regardless of gender or age: 5.98% (111 of 1,857)
• people who take Atorvastatin Calcium and have Muscle Fatigue:
  - among males aged 59 (±5) who take Atorvastatin Calcium and have side effects: 5.35% (353 of 6,599)
  - among people who take Atorvastatin Calcium and have side effects, regardless of gender or age: 5.15% (3,746 of 72,761)
• people who take Asa and have Muscle Fatigue:
  - among males aged 59 (±5) who take Asa and have side effects: 5.15% (157 of 3,051)
  - among people who take Asa and have side effects, regardless of gender or age: 6.12% (1,961 of 32,022)
• people who take Atorvastatin Calcium and have Muscle Spasm:
  - among males aged 59 (±5) who take Atorvastatin Calcium and have side effects: 2.03% (134 of 6,599)
  - among people who take Atorvastatin Calcium and have side effects, regardless of gender or age: 2.34% (1,704 of 72,761)
• people who take Asa and have Muscle Spasm:
  - among males aged 59 (±5) who take Asa and have side effects: 1.77% (54 of 3,051)
  - among people who take Asa and have side effects, regardless of gender or age: 1.97% (632 of 32,022)
• people who take Pregabalin and have Muscle Spasm:
  - among males aged 59 (±5) who take Pregabalin and have side effects: 1.42% (77 of 5,416)
  - among people who take Pregabalin and have side effects, regardless of gender or age: 1.79% (1,311 of 73,061)
• people who take Venlafaxine Hydrochloride and have Muscle Spasm:
  - among males aged 59 (±5) who take Venlafaxine Hydrochloride and have side effects: 1.27% (10 of 790)
  - among people who take Venlafaxine Hydrochloride and have side effects, regardless of gender or age: 1.64% (253 of 15,425)
• people who take Lorazepam and have Muscle Spasm:
  - among males aged 59 (±5) who take Lorazepam and have side effects: 1.12% (120 of 10,703)
  - among people who take Lorazepam and have side effects, regardless of gender or age: 1.63% (2,643 of 161,735)
• people who take Vyvanse and have Muscle Spasm:
  - among males aged 59 (±5) who take Vyvanse and have side effects: 3.34% (10 of 299)
  - among people who take Vyvanse and have side effects, regardless of gender or age: 1.41% (396 of 28,085)
• people who take Terazosin Hydrochloride and have Muscle Spasm:
  - among males aged 59 (±5) who take Terazosin Hydrochloride and have side effects: 2.06% (5 of 243)
  - among people who take Terazosin Hydrochloride and have side effects, regardless of gender or age: 1.62% (30 of 1,857)
• people who take Lorazepam and have Orthostatic Hypotension:
  - among males aged 59 (±5) who take Lorazepam and have side effects: 0.2% (21 of 10,703)
  - among people who take Lorazepam and have side effects, regardless of gender or age: 0.28% (449 of 161,735)
• people who take Asa and have Orthostatic Hypotension:
  - among males aged 59 (±5) who take Asa and have side effects: 0.98% (30 of 3,051)
  - among people who take Asa and have side effects, regardless of gender or age: 0.3% (97 of 32,022)
• people who take Vyvanse and have Orthostatic Hypotension:
  - among males aged 59 (±5) who take Vyvanse and have side effects: 0% (0 of 299)
  - among people who take Vyvanse and have side effects, regardless of gender or age: 0.05% (15 of 28,085)
• people who take Terazosin Hydrochloride and have Orthostatic Hypotension:
  - among males aged 59 (±5) who take Terazosin Hydrochloride and have side effects: 3.7% (9 of 243)
  - among people who take Terazosin Hydrochloride and have side effects, regardless of gender or age: 1.83% (34 of 1,857)
• people who take Atorvastatin Calcium and have Orthostatic Hypotension:
  - among males aged 59 (±5) who take Atorvastatin Calcium and have side effects: 0.15% (10 of 6,599)
  - among people who take Atorvastatin Calcium and have side effects, regardless of gender or age: 0.2% (142 of 72,761)
• people who take Venlafaxine Hydrochloride and have Orthostatic Hypotension:
  - among males aged 59 (±5) who take Venlafaxine Hydrochloride and have side effects: 0% (0 of 790)
  - among people who take Venlafaxine Hydrochloride and have side effects, regardless of gender or age: 0.31% (48 of 15,425)
• people who take Pregabalin and have Orthostatic Hypotension:
  - among males aged 59 (±5) who take Pregabalin and have side effects: 0.13% (7 of 5,416)
  - among people who take Pregabalin and have side effects, regardless of gender or age: 0.16% (116 of 73,061)

Common drug interactions *:

1. Pain In Extremity : 8 people, 47.06%
2. Back Pain : 8 people, 47.06%
3. Urinary Tract Infection : 7 people, 41.18%
4. Rashes (redness): 7 people, 41.18%
5. Weakness : 6 people, 35.29%
6. Spinal Osteoarthritis (joint cartilage loss in spine): 6 people, 35.29%
7. Nausea (feeling of having an urge to vomit): 6 people, 35.29%
8. Chest Pain : 6 people, 35.29%
9. Diarrhea : 6 people, 35.29%
10. Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 35.29%
11. Hypotension (abnormally low blood pressure): 6 people, 35.29%
12. Dyspnea (difficult or laboured breathing): 6 people, 35.29%
13. Fainting (loss of consciousness and postural tone): 6 people, 35.29%
14. Osteonecrosis Of Jaw (death of bone of jaw): 5 people, 29.41%
15. Herpes Zoster : 5 people, 29.41%
16. Infection : 5 people, 29.41%
17. Injury : 5 people, 29.41%
18. Dehydration (dryness resulting from the removal of water): 5 people, 29.41%
19. Constipation : 5 people, 29.41%
20. Headache (pain in head): 5 people, 29.41%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 52.94%
2. Inflammation : 7 people, 41.18%
3. Nausea (feeling of having an urge to vomit): 7 people, 41.18%
4. Asthma : 7 people, 41.18%
5. Cardiac Disorder : 5 people, 29.41%
6. Neuropathy Peripheral (surface nerve damage): 5 people, 29.41%
7. Gastrointestinal Motility Disorder (abnormal intestinal contractions): 4 people, 23.53%
8. Gastric Ulcer (stomach ulcer): 4 people, 23.53%
9. Hypersensitivity : 4 people, 23.53%
10. Overgrowth Bacterial (extra growth due to bacteria): 4 people, 23.53%
11. Heart Disease : 4 people, 23.53%
12. Prostatic Disorder : 4 people, 23.53%
13. Prostatomegaly (enlargement of the prostate): 4 people, 23.53%
14. Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 4 people, 23.53%
15. Constipation : 4 people, 23.53%
16. Sleep Disorder : 4 people, 23.53%
17. Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 4 people, 23.53%
18. Diarrhea : 3 people, 17.65%
19. Fungal Infection : 3 people, 17.65%
20. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 17.65%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

1. Abilify (9 people, 52.94%)
2. Lunesta (8 people, 47.06%)
3. Cymbalta (7 people, 41.18%)
4. Ondansetron (7 people, 41.18%)
5. Zometa (5 people, 29.41%)
6. Prevacid (5 people, 29.41%)
7. Aredia (5 people, 29.41%)
8. Fosamax (5 people, 29.41%)
9. Gabapentin (5 people, 29.41%)
10. Norco (5 people, 29.41%)
11. Pantoprazole (5 people, 29.41%)
12. Prednisone (5 people, 29.41%)
13. Lotensin (5 people, 29.41%)
14. Zantac (5 people, 29.41%)
15. Megace (4 people, 23.53%)
16. Klor-Con (4 people, 23.53%)
17. Nasonex (4 people, 23.53%)
18. Zocor (4 people, 23.53%)
19. Miralax (4 people, 23.53%)
20. Avodart (4 people, 23.53%)

Drug effectiveness *:

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