A study for a 30 year old woman who takes Zoloft, Modafinil, Methylphenidate Hydrochloride (an AI-powered real world drug study)

Summary:

588 females aged 30 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 30 year old female patient who has Cataplexy, Narcolepsy. The study is created by eHealthMe based on reports from sources including the FDA.


On Sep, 15, 2025

588 females aged 30 (±5) who take Zoloft, Modafinil, Methylphenidate Hydrochloride and have adverse effects are studied.


Number of reports submitted per year:

Zoloft, Modafinil, Methylphenidate Hydrochloride for a 30-year old woman.

Information of the patient in this study:

  • Age: 30
  • Gender: female
  • Conditions: Cataplexy, Narcolepsy
  • Drugs taken:
    • Zoloft (sertraline hydrochloride)
    • Methylphenidate Hydrochloride (methylphenidate hydrochloride)
    • Modafinil (modafinil)

Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

  • Nystagmus (a condition of involuntary eye movement):
    - among females aged 30 (±5) who take the same drugs: 0% (0 of 588)
    - among people who take the same drugs, regardless of gender or age: 0% (0 of 9,877)

By each condition:

  • people who have Nystagmus with Cataplexy:
    - among females aged 30 (±5) who have Cataplexy: 0.04% (1 of 2,755)
    - among people who have Cataplexy, regardless of gender or age: 0.01% (5 of 40,682)
  • people who have Nystagmus with Narcolepsy:
    - among females aged 30 (±5) who have Narcolepsy: 0.04% (2 of 5,395)
    - among people who have Narcolepsy, regardless of gender or age: 0.01% (9 of 76,205)

By each drug (FDA data only):

  • people who take Zoloft and have Nystagmus:
    - among females aged 30 (±5) who take Zoloft and have side effects: 0.08% (6 of 7,974)
    - among people who take Zoloft and have side effects, regardless of gender or age: 0.06% (73 of 128,192)
  • people who take Methylphenidate Hydrochloride and have Nystagmus:
    - among females aged 30 (±5) who take Methylphenidate Hydrochloride and have side effects: 0% (0 of 262)
    - among people who take Methylphenidate Hydrochloride and have side effects, regardless of gender or age: 0.14% (9 of 6,367)
  • people who take Modafinil and have Nystagmus:
    - among females aged 30 (±5) who take Modafinil and have side effects: 0% (0 of 1,103)
    - among people who take Modafinil and have side effects, regardless of gender or age: 0.09% (18 of 19,892)

Common drug interactions *:

  1. Nausea (feeling of having an urge to vomit): 80 people, 13.61%
  2. Drug Ineffective : 50 people, 8.50%
  3. Weight Decreased : 49 people, 8.33%
  4. Headache (pain in head): 49 people, 8.33%
  5. Pain : 49 people, 8.33%
  6. High Blood Pressure : 45 people, 7.65%
  7. Rashes (redness): 43 people, 7.31%
  8. Nausea And Vomiting : 40 people, 6.80%
  9. Back Pain : 38 people, 6.46%
  10. Tremor (trembling or shaking movements in one or more parts of your body): 37 people, 6.29%
  11. Panic Disorder : 37 people, 6.29%
  12. Dizziness : 32 people, 5.44%
  13. Malaise (a feeling of general discomfort or uneasiness): 31 people, 5.27%
  14. Feeling Abnormal : 30 people, 5.10%
  15. Joint Pain : 30 people, 5.10%
  16. Sleep Walking (walking during sleep): 29 people, 4.93%
  17. Pain In Extremity : 28 people, 4.76%
  18. Emotional Distress : 27 people, 4.59%
  19. Insomnia (sleeplessness): 25 people, 4.25%
  20. Suicidal Ideation : 25 people, 4.25%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 65 people, 11.05%
  2. Bipolar Disorder (mood disorder): 30 people, 5.10%
  3. Birth Control : 27 people, 4.59%
  4. Pain : 27 people, 4.59%
  5. Migraine (headache): 20 people, 3.40%
  6. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 18 people, 3.06%
  7. Burnout Syndrome (problems related to life-management difficulty, but not considered a ""disorder): 16 people, 2.72%
  8. Insomnia (sleeplessness): 15 people, 2.55%
  9. Sleep Disorder : 10 people, 1.70%
  10. Nausea (feeling of having an urge to vomit): 9 people, 1.53%
  11. Muscle Spasms (muscle contraction): 9 people, 1.53%
  12. Rickets (softening of bones): 8 people, 1.36%
  13. Breakthrough Pain : 7 people, 1.19%
  14. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 7 people, 1.19%
  15. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 1.19%
  16. Headache (pain in head): 7 people, 1.19%
  17. Asthma : 7 people, 1.19%
  18. Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 1.19%
  19. Seasonal Allergy (allergic condition due to certain season): 6 people, 1.02%
  20. Rashes (redness): 5 people, 0.85%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

  1. Xyrem (288 people, 48.98%)
  2. Adderall (91 people, 15.48%)
  3. Nuvigil (68 people, 11.56%)
  4. Vitamin D3 (65 people, 11.05%)
  5. Lyrica (59 people, 10.03%)
  6. Wellbutrin (57 people, 9.69%)
  7. Proair Hfa (53 people, 9.01%)
  8. Xanax (46 people, 7.82%)
  9. Zyrtec (42 people, 7.14%)
  10. Buspirone Hcl (41 people, 6.97%)
  11. Klonopin (39 people, 6.63%)
  12. Topamax (36 people, 6.12%)
  13. Vitamin B12 (35 people, 5.95%)
  14. Lamictal (34 people, 5.78%)
  15. Epipen (32 people, 5.44%)
  16. Cymbalta (32 people, 5.44%)
  17. Singulair (32 people, 5.44%)
  18. Biotin (31 people, 5.27%)
  19. Ambien (31 people, 5.27%)
  20. Abilify (31 people, 5.27%)

Drug effectiveness *:

Zoloft:
  • not at all: 0 %
  • somewhat: 40 %
  • moderate: 40 %
  • high: 20 %
  • very high: 0 %
Modafinil:
  • not at all: 0 %
  • somewhat: 0 %
  • moderate: 100 %
  • high: 0 %
  • very high: 0 %
Methylphenidate Hydrochloride:
  • not at all: 0 %
  • somewhat: 0 %
  • moderate: 0 %
  • high: 66.67 %
  • very high: 33.33 %

* Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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Treatments, associated medications and conditions:

Drug side effects:

Drug interactions:

Symptoms:

Drugs that are associated with:

Conditions that are associated with:

How the phase IV clinical study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.