A study for a 70 year old man who takes Amlodipine Besylate, Rosuvastatin Calcium, Allopurinol, Metoprolol Tartrate, Hydrochlorothiazide, Benazepril Hydrochloride (an AI-powered real world drug study)

---

---

Number of reports submitted per year:

Information of the patient in this study:

• Age: 70
• Gender: male
• Conditions: Gout, Hypertension
• Drugs taken:
  • Amlodipine Besylate (amlodipine besylate)
  • Rosuvastatin Calcium (rosuvastatin calcium)
  • Allopurinol (allopurinol)
  • Metoprolol Tartrate (metoprolol tartrate)
  • Hydrochlorothiazide (hydrochlorothiazide)
  • Benazepril Hydrochloride (benazepril hydrochloride)

---

Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

• Tachycardia (a heart rate that exceeds the range of 100 beats/min):
  - among males aged 70 (±5) who take the same drugs: 0% (0 of 16)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 129)

By each condition:

• people who have Tachycardia with Hypertension:
  - among males aged 70 (±5) who have Hypertension: 1.07% (759 of 70,953)
  - among people who have Hypertension, regardless of gender or age: 1.32% (8,014 of 608,860)
• people who have Tachycardia with Gout:
  - among males aged 70 (±5) who have Gout: 0.81% (49 of 6,041)
  - among people who have Gout, regardless of gender or age: 0.81% (261 of 32,032)

By each drug (FDA data only):

• people who take Amlodipine Besylate and have Tachycardia:
  - among males aged 70 (±5) who take Amlodipine Besylate and have side effects: 0.83% (61 of 7,385)
  - among people who take Amlodipine Besylate and have side effects, regardless of gender or age: 0.99% (706 of 71,612)
• people who take Rosuvastatin Calcium and have Tachycardia:
  - among males aged 70 (±5) who take Rosuvastatin Calcium and have side effects: 1.71% (47 of 2,753)
  - among people who take Rosuvastatin Calcium and have side effects, regardless of gender or age: 1.09% (269 of 24,757)
• people who take Allopurinol and have Tachycardia:
  - among males aged 70 (±5) who take Allopurinol and have side effects: 1.39% (464 of 33,361)
  - among people who take Allopurinol and have side effects, regardless of gender or age: 1.33% (2,502 of 188,151)
• people who take Metoprolol Tartrate and have Tachycardia:
  - among males aged 70 (±5) who take Metoprolol Tartrate and have side effects: 1.7% (169 of 9,968)
  - among people who take Metoprolol Tartrate and have side effects, regardless of gender or age: 1.66% (1,384 of 83,478)
• people who take Hydrochlorothiazide and have Tachycardia:
  - among males aged 70 (±5) who take Hydrochlorothiazide and have side effects: 1.16% (181 of 15,604)
  - among people who take Hydrochlorothiazide and have side effects, regardless of gender or age: 1.65% (2,932 of 177,585)
• people who take Benazepril Hydrochloride and have Tachycardia:
  - among males aged 70 (±5) who take Benazepril Hydrochloride and have side effects: 3.73% (19 of 510)
  - among people who take Benazepril Hydrochloride and have side effects, regardless of gender or age: 1.61% (76 of 4,711)

Common drug interactions *:

1. Acute Kidney Failure : 7 people, 43.75%
2. Chronic Kidney Disease : 6 people, 37.50%
3. Interstitial Nephritis (inflammation of the kidney): 4 people, 25.00%
4. Skin Cancer : 4 people, 25.00%
5. Renal Injury (kidney injury): 4 people, 25.00%
6. Oedema Peripheral (superficial swelling): 3 people, 18.75%
7. Hyperkalemia (damage to or disease of the kidney): 3 people, 18.75%
8. Loss Of Consciousness : 3 people, 18.75%
9. Hyperhidrosis (abnormally increased sweating): 3 people, 18.75%
10. Nephrogenic Anaemia (anaemia due to kidney disease): 3 people, 18.75%
11. Hypotension (abnormally low blood pressure): 3 people, 18.75%
12. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 3 people, 18.75%
13. Renal Disorder (kidney disease): 3 people, 18.75%
14. Cardiac Murmur (an heart sound in valve abnormality): 3 people, 18.75%
15. Blood Creatinine Increased : 3 people, 18.75%
16. Nosebleed (bleeding from nose): 2 people, 12.50%
17. Emotional Distress : 1 person, 6.25%
18. Faeces Hard : 1 person, 6.25%
19. Change Of Bowel Habit : 1 person, 6.25%
20. Balance Disorder : 1 person, 6.25%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 37.50%
2. Renal Disorder (kidney disease): 5 people, 31.25%
3. Pain : 5 people, 31.25%
4. Anaemia (lack of blood): 4 people, 25.00%
5. Sleep Disorder : 3 people, 18.75%
6. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 18.75%
7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 12.50%
8. Cardiac Disorder : 2 people, 12.50%
9. Oesophageal Irritation : 1 person, 6.25%
10. Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%
11. Irritable Bowel Syndrome : 1 person, 6.25%
12. Hyperthyroidism (over activity of the thyroid gland): 1 person, 6.25%
13. Diarrhea : 1 person, 6.25%
14. Diabetes : 1 person, 6.25%
15. Chest Pain : 1 person, 6.25%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

1. Plavix (8 people, 50.00%)
2. Pravachol (7 people, 43.75%)
3. Cozaar (7 people, 43.75%)
4. Aspirin (7 people, 43.75%)
5. Prilosec (7 people, 43.75%)
6. Fish Oil (7 people, 43.75%)
7. Prevacid (6 people, 37.50%)
8. Lipitor (6 people, 37.50%)
9. Vitamin D (6 people, 37.50%)
10. Furosemide (6 people, 37.50%)
11. Gabapentin (6 people, 37.50%)
12. Spironolactone (6 people, 37.50%)
13. Tylenol (5 people, 31.25%)
14. Nexium (5 people, 31.25%)
15. Protonix (5 people, 31.25%)
16. Tamsulosin (5 people, 31.25%)
17. Diovan (5 people, 31.25%)
18. Capoten (4 people, 25.00%)
19. Bumex (4 people, 25.00%)
20. Celebrex (4 people, 25.00%)

Drug effectiveness *:

---