A study for a 61 year old woman who takes Seroquel, Valdoxan, Cymbalta, Lithium Citrate (an AI-powered real world drug study)

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Number of reports submitted per year:

Information of the patient in this study:

• Age: 61
• Gender: female
• Conditions: Major Depression, Drug Resistance
• Drugs taken:
  • Valdoxan (agomelatine)
  • Cymbalta (duloxetine hydrochloride)
  • Seroquel (quetiapine fumarate)
  • Lithium Citrate (lithium citrate)

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Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

• Muscle Weakness (a lack of muscle strength):
  - among females aged 61 (±5) who take the same drugs: 0% (0 of 14)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 316)
• Muscle Spasm:
  - among females aged 61 (±5) who take the same drugs: 0% (0 of 14)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 316)
• Joint Pain:
  - among females aged 61 (±5) who take the same drugs: 0% (0 of 14)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 316)
• Tiredness:
  - among females aged 61 (±5) who take the same drugs: 0% (0 of 14)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 316)
• Nausea (feeling of having an urge to vomit):
  - among females aged 61 (±5) who take the same drugs: 0% (0 of 14)
  - among people who take the same drugs, regardless of gender or age: 0% (0 of 316)

By each condition:

• people who have Joint Pain with Major Depression:
  - among females aged 61 (±5) who have Major Depression: 1.44% (42 of 2,921)
  - among people who have Major Depression, regardless of gender or age: 0.9% (285 of 31,832)
• people who have Joint Pain with Drug Resistance:
  - among females aged 61 (±5) who have Drug Resistance: 0% (0 of 13)
  - among people who have Drug Resistance, regardless of gender or age: 0.74% (2 of 270)
• people who have Muscle Spasm with Major Depression:
  - among females aged 61 (±5) who have Major Depression: 1.4% (41 of 2,921)
  - among people who have Major Depression, regardless of gender or age: 0.89% (282 of 31,832)
• people who have Muscle Spasm with Drug Resistance:
  - among females aged 61 (±5) who have Drug Resistance: 0% (0 of 13)
  - among people who have Drug Resistance, regardless of gender or age: 0% (0 of 270)
• people who have Muscle Weakness with Major Depression:
  - among females aged 61 (±5) who have Major Depression: 3.05% (89 of 2,921)
  - among people who have Major Depression, regardless of gender or age: 2.34% (745 of 31,832)
• people who have Muscle Weakness with Drug Resistance:
  - among females aged 61 (±5) who have Drug Resistance: 38.46% (5 of 13)
  - among people who have Drug Resistance, regardless of gender or age: 3.33% (9 of 270)
• people who have Nausea with Major Depression:
  - among females aged 61 (±5) who have Major Depression: 6.03% (176 of 2,921)
  - among people who have Major Depression, regardless of gender or age: 5.79% (1,843 of 31,832)
• people who have Nausea with Drug Resistance:
  - among females aged 61 (±5) who have Drug Resistance: 53.85% (7 of 13)
  - among people who have Drug Resistance, regardless of gender or age: 4.44% (12 of 270)
• people who have Tiredness with Major Depression:
  - among females aged 61 (±5) who have Major Depression: 4.28% (125 of 2,921)
  - among people who have Major Depression, regardless of gender or age: 3.52% (1,119 of 31,832)
• people who have Tiredness with Drug Resistance:
  - among females aged 61 (±5) who have Drug Resistance: 0% (0 of 13)
  - among people who have Drug Resistance, regardless of gender or age: 2.96% (8 of 270)

By each drug (FDA data only):

• people who take Valdoxan and have Joint Pain:
  - among females aged 61 (±5) who take Valdoxan and have side effects: 3.28% (2 of 61)
  - among people who take Valdoxan and have side effects, regardless of gender or age: 6.38% (39 of 611)
• people who take Seroquel and have Joint Pain:
  - among females aged 61 (±5) who take Seroquel and have side effects: 2.77% (243 of 8,759)
  - among people who take Seroquel and have side effects, regardless of gender or age: 1.81% (2,062 of 113,632)
• people who take Cymbalta and have Joint Pain:
  - among females aged 61 (±5) who take Cymbalta and have side effects: 6.7% (1,294 of 19,322)
  - among people who take Cymbalta and have side effects, regardless of gender or age: 4.82% (7,001 of 145,283)
• people who take Lithium Citrate and have Joint Pain:
  - among females aged 61 (±5) who take Lithium Citrate and have side effects: 0% (0 of 21)
  - among people who take Lithium Citrate and have side effects, regardless of gender or age: 0.77% (3 of 389)
• people who take Cymbalta and have Muscle Spasm:
  - among females aged 61 (±5) who take Cymbalta and have side effects: 2.43% (469 of 19,322)
  - among people who take Cymbalta and have side effects, regardless of gender or age: 2.1% (3,049 of 145,283)
• people who take Seroquel and have Muscle Spasm:
  - among females aged 61 (±5) who take Seroquel and have side effects: 1.69% (148 of 8,759)
  - among people who take Seroquel and have side effects, regardless of gender or age: 1.24% (1,404 of 113,632)
• people who take Valdoxan and have Muscle Spasm:
  - among females aged 61 (±5) who take Valdoxan and have side effects: 0% (0 of 61)
  - among people who take Valdoxan and have side effects, regardless of gender or age: 1.96% (12 of 611)
• people who take Lithium Citrate and have Muscle Spasm:
  - among females aged 61 (±5) who take Lithium Citrate and have side effects: 0% (0 of 21)
  - among people who take Lithium Citrate and have side effects, regardless of gender or age: 0.77% (3 of 389)
• people who take Cymbalta and have Muscle Weakness:
  - among females aged 61 (±5) who take Cymbalta and have side effects: 6.8% (1,314 of 19,322)
  - among people who take Cymbalta and have side effects, regardless of gender or age: 4.89% (7,110 of 145,283)
• people who take Seroquel and have Muscle Weakness:
  - among females aged 61 (±5) who take Seroquel and have side effects: 3.72% (326 of 8,759)
  - among people who take Seroquel and have side effects, regardless of gender or age: 2.91% (3,304 of 113,632)
• people who take Lithium Citrate and have Muscle Weakness:
  - among females aged 61 (±5) who take Lithium Citrate and have side effects: 9.52% (2 of 21)
  - among people who take Lithium Citrate and have side effects, regardless of gender or age: 1.54% (6 of 389)
• people who take Valdoxan and have Muscle Weakness:
  - among females aged 61 (±5) who take Valdoxan and have side effects: 21.31% (13 of 61)
  - among people who take Valdoxan and have side effects, regardless of gender or age: 10.64% (65 of 611)
• people who take Cymbalta and have Nausea:
  - among females aged 61 (±5) who take Cymbalta and have side effects: 12.24% (2,365 of 19,322)
  - among people who take Cymbalta and have side effects, regardless of gender or age: 11.37% (16,520 of 145,283)
• people who take Lithium Citrate and have Nausea:
  - among females aged 61 (±5) who take Lithium Citrate and have side effects: 4.76% (1 of 21)
  - among people who take Lithium Citrate and have side effects, regardless of gender or age: 3.86% (15 of 389)
• people who take Seroquel and have Nausea:
  - among females aged 61 (±5) who take Seroquel and have side effects: 5.85% (512 of 8,759)
  - among people who take Seroquel and have side effects, regardless of gender or age: 4.3% (4,890 of 113,632)
• people who take Valdoxan and have Nausea:
  - among females aged 61 (±5) who take Valdoxan and have side effects: 1.64% (1 of 61)
  - among people who take Valdoxan and have side effects, regardless of gender or age: 7.86% (48 of 611)
• people who take Cymbalta and have Tiredness:
  - among females aged 61 (±5) who take Cymbalta and have side effects: 10.96% (2,118 of 19,322)
  - among people who take Cymbalta and have side effects, regardless of gender or age: 10.53% (15,305 of 145,283)
• people who take Seroquel and have Tiredness:
  - among females aged 61 (±5) who take Seroquel and have side effects: 6.3% (552 of 8,759)
  - among people who take Seroquel and have side effects, regardless of gender or age: 4.99% (5,667 of 113,632)
• people who take Valdoxan and have Tiredness:
  - among females aged 61 (±5) who take Valdoxan and have side effects: 39.34% (24 of 61)
  - among people who take Valdoxan and have side effects, regardless of gender or age: 13.91% (85 of 611)
• people who take Lithium Citrate and have Tiredness:
  - among females aged 61 (±5) who take Lithium Citrate and have side effects: 0% (0 of 21)
  - among people who take Lithium Citrate and have side effects, regardless of gender or age: 3.86% (15 of 389)

Common drug interactions *:

1. Weight Increased : 3 people, 21.43%
2. Dyskinesia (abnormality or impairment of voluntary movement): 3 people, 21.43%
3. Nausea (feeling of having an urge to vomit): 3 people, 21.43%
4. Nausea And Vomiting : 2 people, 14.29%
5. Fatigue (feeling of tiredness): 2 people, 14.29%
6. Drug Ineffective : 2 people, 14.29%
7. Drowsiness : 2 people, 14.29%
8. Diarrhea : 2 people, 14.29%
9. Pain In Extremity : 2 people, 14.29%
10. Agitation (state of anxiety or nervous excitement): 2 people, 14.29%
11. Chronic Kidney Disease : 2 people, 14.29%
12. Thinking Abnormal : 2 people, 14.29%
13. Suicidal Ideation : 2 people, 14.29%
14. Consciousness - Decreased : 1 person, 7.14%
15. Drug Hypersensitivity : 1 person, 7.14%
16. Hallucination, Visual (seeing things that aren't there): 1 person, 7.14%
17. Gait Disturbance : 1 person, 7.14%
18. Dyspnea (difficult or laboured breathing): 1 person, 7.14%
19. Blindness : 1 person, 7.14%
20. Blood Glucose Increased : 1 person, 7.14%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

1. Sleep Disorder : 4 people, 28.57%
2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 21.43%
3. Pain : 2 people, 14.29%
4. Migraine (headache): 2 people, 14.29%
5. High Blood Cholesterol : 2 people, 14.29%
6. Overdose : 1 person, 7.14%
7. Mood Swings (an extreme or rapid change in mood): 1 person, 7.14%
8. Mania (a state of abnormally elevated or irritable mood): 1 person, 7.14%
9. Infection : 1 person, 7.14%
10. Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 1 person, 7.14%
11. Constipation : 1 person, 7.14%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

1. Abilify (3 people, 21.43%)
2. Prilosec (3 people, 21.43%)
3. Nexium (3 people, 21.43%)
4. Clonazepam (2 people, 14.29%)
5. Prevacid (2 people, 14.29%)
6. Singulair (2 people, 14.29%)
7. Geodon (2 people, 14.29%)
8. Fluoxetine (2 people, 14.29%)
9. Lipitor (2 people, 14.29%)
10. Xanax (2 people, 14.29%)
11. Zyprexa (2 people, 14.29%)
12. Linzess (1 person, 7.14%)
13. Levoxyl (1 person, 7.14%)
14. Lantus (1 person, 7.14%)
15. Lovaza (1 person, 7.14%)
16. Lamictal (1 person, 7.14%)
17. Klonopin (1 person, 7.14%)
18. Janumet (1 person, 7.14%)
19. Hydroxyzine (1 person, 7.14%)
20. Lyrica (1 person, 7.14%)

Drug effectiveness *:

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