A study for a 74 year old man who takes Metoprolol Succinate, Losartan Potassium And Hydrochlorothiazide, Tramadol (an AI-powered real world drug study)
Summary:
1,839 males aged 74 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 74 year old male patient who has Low Blood Pressure, High Arch, Arthritis. The study is created by eHealthMe based on reports from sources including the FDA.
1,839 males aged 74 (±5) who take Metoprolol Succinate, Losartan Potassium And Hydrochlorothiazide, Tramadol and have adverse effects are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 74
- Gender: male
- Conditions: Low Blood Pressure, High Arch, Arthritis
- Drugs taken:
- Metoprolol Succinate (metoprolol succinate)
- Losartan Potassium And Hydrochlorothiazide (hydrochlorothiazide; losartan potassium)
- Tramadol (tramadol hydrochloride)
Common drug interactions *:
- Fatigue (feeling of tiredness): 175 people, 9.52%
- Weakness : 160 people, 8.70%
- Acute Kidney Failure : 137 people, 7.45%
- Dyspnea (difficult or laboured breathing): 125 people, 6.80%
- Pneumonia : 122 people, 6.63%
- Chronic Kidney Disease : 119 people, 6.47%
- Nausea (feeling of having an urge to vomit): 110 people, 5.98%
- Diarrhea : 106 people, 5.76%
- Death : 102 people, 5.55%
- Dizziness : 95 people, 5.17%
- Fall : 88 people, 4.79%
- Chest Pain : 73 people, 3.97%
- Weight Decreased : 73 people, 3.97%
- Nausea And Vomiting : 70 people, 3.81%
- Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 69 people, 3.75%
- Dehydration (dryness resulting from the removal of water): 66 people, 3.59%
- Constipation : 65 people, 3.53%
- Confusional State : 60 people, 3.26%
- Thrombocytopenia (decrease of platelets in blood): 59 people, 3.21%
- Anaemia (lack of blood): 58 people, 3.15%
Common co-existing conditions *:
You may use this to check any potential undetected conditions.
- Multiple Myeloma (cancer of the plasma cells): 218 people, 11.85%
- High Blood Cholesterol : 201 people, 10.93%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 181 people, 9.84%
- Diabetes : 131 people, 7.12%
- Nausea (feeling of having an urge to vomit): 113 people, 6.14%
- Cardiac Disorder : 110 people, 5.98%
- Constipation : 91 people, 4.95%
- Depression : 80 people, 4.35%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 78 people, 4.24%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 70 people, 3.81%
- Type 2 Diabetes : 69 people, 3.75%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 61 people, 3.32%
- Prostate Cancer : 61 people, 3.32%
- Stress And Anxiety : 59 people, 3.21%
- Enlarged Prostate : 57 people, 3.10%
- Insomnia (sleeplessness): 56 people, 3.05%
- Hyperlipidaemia (presence of excess lipids in the blood): 55 people, 2.99%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 53 people, 2.88%
- Gout (uric acid crystals building up in the body): 49 people, 2.66%
- Indigestion : 49 people, 2.66%
Common co-used drugs *:
You may use this to check any potential interacting drugs.
- Amlodipine (268 people, 14.57%)
- Aspirin (253 people, 13.76%)
- Lasix (216 people, 11.75%)
- Tamsulosin (203 people, 11.04%)
- Lipitor (200 people, 10.88%)
- Plavix (186 people, 10.11%)
- Metformin (184 people, 10.01%)
- Tylenol (170 people, 9.24%)
- Revlimid (165 people, 8.97%)
- Pantoprazole (164 people, 8.92%)
- Protonix (151 people, 8.21%)
- Vitamin D3 (149 people, 8.10%)
- Nexium (145 people, 7.88%)
- Xarelto (140 people, 7.61%)
- Eliquis (139 people, 7.56%)
- Flomax (136 people, 7.40%)
- Allopurinol (134 people, 7.29%)
- Ondansetron (134 people, 7.29%)
- Furosemide (130 people, 7.07%)
- Prilosec (128 people, 6.96%)
Drug effectiveness *:
Metoprolol Succinate:
- not at all: 0 %
- somewhat: 0 %
- moderate: 75 %
- high: 25 %
- very high: 0 %
Losartan Potassium And Hydrochlorothiazide:
- not at all: 0 %
- somewhat: 0 %
- moderate: 0 %
- high: 100 %
- very high: 0 %
Tramadol:
- not at all: 0 %
- somewhat: 0 %
- moderate: 50 %
- high: 50 %
- very high: 0 %
* Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Drug side effects in long term, by gender and age:
- Losartan potassium and hydrochlorothiazide: 2,181 reports
- Metoprolol succinate: 66,853 reports
- Tramadol: 235,773 reports
Treatments, associated medications and conditions:
- Arthritis: 188,604 reports
- High arch: 373 reports
- Low blood pressure: 329,842 reports
Drug interactions:
- Metoprolol succinate and Losartan potassium and hydrochlorothiazide drug interaction (51 reports)
- Metoprolol succinate and Tramadol drug interaction (3,387 reports)
- Losartan potassium and hydrochlorothiazide and Tramadol drug interaction (51 reports)
How the phase IV clinical study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.