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A study for a 58 year old woman who takes Tamoxifen Citrate (an AI-powered real world drug study)

Summary:

6,475 females aged 58 (±5) who take the same drug and have adverse effects are studied. This is a phase IV clinical study for a 58 year old female patient who has Breast Cancer Stage I. The study is created by eHealthMe based on reports from sources including the FDA.


On Aug, 18, 2026

6,475 females aged 58 (±5) who take Tamoxifen Citrate and have adverse effects are studied.


Number of reports submitted per year:

Tamoxifen Citrate for a 58-year old woman.

Information of the patient in this study:

  • Age: 58
  • Gender: female

What are the drugs?

What are the conditions?

What are the adverse effects?

  • Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night) is found to be associated with 985 drugs and 971 conditions by eHealthMe. Check the latest studies of Middle insomnia.

Comparison with patient's specific adverse outcomes:

You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.

By the same drug(s):

  • Middle Insomnia (difficulty returning to sleep after awakening either in the middle of the night):
    - among females aged 58 (±5) who take the same drug: 0.05% (3 of 6,475)
    - among people who take the same drug, regardless of gender or age: 0.04% (14 of 34,825)

By each condition:

  • people who have Middle Insomnia with Breast Cancer Stage I:
    - among females aged 58 (±5) who have Breast Cancer Stage I: 0% (0 of 142)
    - among people who have Breast Cancer Stage I, regardless of gender or age: 0% (0 of 628)

By each drug (FDA data only):

  • people who take Tamoxifen Citrate and have Middle Insomnia:
    - among females aged 58 (±5) who take Tamoxifen Citrate and have side effects: 0.13% (3 of 2,264)
    - among people who take Tamoxifen Citrate and have side effects, regardless of gender or age: 0.13% (14 of 10,731)

Common side effects *:

  1. Pain : 593 people, 9.16%
  2. Fatigue (feeling of tiredness): 564 people, 8.71%
  3. Stress And Anxiety : 538 people, 8.31%
  4. Nausea (feeling of having an urge to vomit): 535 people, 8.26%
  5. Hair Loss : 474 people, 7.32%
  6. Malignant Neoplasm Progression (cancer tumour came back): 455 people, 7.03%
  7. Joint Pain : 453 people, 7.00%
  8. Weakness : 446 people, 6.89%
  9. Metastases To Bone (cancer spreads to bone): 397 people, 6.13%
  10. Dyspnea (difficult or laboured breathing): 358 people, 5.53%
  11. Dizziness : 342 people, 5.28%
  12. Bone Disorder : 339 people, 5.24%
  13. Osteonecrosis Of Jaw (death of bone of jaw): 334 people, 5.16%
  14. Headache (pain in head): 306 people, 4.73%
  15. Back Pain : 302 people, 4.66%
  16. Rashes (redness): 285 people, 4.40%
  17. Anaemia (lack of blood): 284 people, 4.39%
  18. Depression : 281 people, 4.34%
  19. Diarrhea : 277 people, 4.28%
  20. High Blood Pressure : 271 people, 4.19%

Common co-existing conditions *:

You may use this to check any potential undetected conditions.

  1. Breast Cancer Metastatic : 547 people, 8.45%
  2. High Blood Pressure : 278 people, 4.29%
  3. Metastases To Bone (cancer spreads to bone): 259 people, 4.00%
  4. Depression : 227 people, 3.51%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 161 people, 2.49%
  6. Pain : 152 people, 2.35%
  7. Neoplasm Malignant (cancer tumour): 117 people, 1.81%
  8. High Blood Cholesterol : 114 people, 1.76%
  9. Stress And Anxiety : 113 people, 1.75%
  10. Osteoporosis (bones weak and more likely to break): 111 people, 1.71%
  11. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 99 people, 1.53%
  12. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 89 people, 1.37%
  13. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 88 people, 1.36%
  14. Diabetes : 69 people, 1.07%
  15. Hot Flush (sudden feelings of heat): 61 people, 0.94%
  16. Insomnia (sleeplessness): 57 people, 0.88%
  17. Breast Cancer Recurrent : 54 people, 0.83%
  18. Asthma : 54 people, 0.83%
  19. Arthritis (form of joint disorder that involves inflammation of one or more joints): 52 people, 0.80%
  20. Type 2 Diabetes : 52 people, 0.80%

Common co-used drugs *:

You may use this to check any potential interacting drugs.

  1. Arimidex (622 people, 9.61%)
  2. Taxotere (610 people, 9.42%)
  3. Zometa (578 people, 8.93%)
  4. Femara (406 people, 6.27%)
  5. Faslodex (373 people, 5.76%)
  6. Herceptin (341 people, 5.27%)
  7. Aredia (332 people, 5.13%)
  8. Aromasin (312 people, 4.82%)
  9. Xeloda (300 people, 4.63%)
  10. Synthroid (294 people, 4.54%)
  11. Letrozole (259 people, 4.00%)
  12. Taxol (253 people, 3.91%)
  13. Cyclophosphamide (244 people, 3.77%)
  14. Ambien (232 people, 3.58%)
  15. Calcium (219 people, 3.38%)
  16. Cytoxan (216 people, 3.34%)
  17. Fosamax (211 people, 3.26%)
  18. Celebrex (200 people, 3.09%)
  19. Nexium (196 people, 3.03%)
  20. Dexamethasone (192 people, 2.97%)

Drug effectiveness *:

Tamoxifen Citrate:
  • not at all: 2.27 %
  • somewhat: 12.88 %
  • moderate: 24.24 %
  • high: 32.58 %
  • very high: 28.03 %

* Some reports may have incomplete information.


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

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Symptoms:

Drugs that are associated with:

Conditions that are associated with:

How the phase IV clinical study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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