Aviane-21 side effects, by duration, gender and age (a phase IV clinical study of FDA data)
Summary:
Side effects are reported by people who take Aviane-21 (ethinyl estradiol; levonorgestrel). Common side effects include malignant melanoma among females.
The phase IV clinical study is created by eHealthMe based on 79 reports from the FDA, and is updated regularly.
What is Aviane-21?
Aviane-21 has active ingredients of ethinyl estradiol; levonorgestrel. It is often used in birth control. eHealthMe is studying from 99 Aviane-21 users. Check the latest studies of Aviane-21.
79 people who take Aviane-21 and have side effects are studied.

What are the common side effects of Aviane-21, by gender? *:
female:
- Malignant melanoma (skin cancer rises from melancytes)
- Abdominal pain
- Drug ineffective
- Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
- Epistaxis (bleed from the nose)
- Hypertension (high blood pressure)
- Abnormal behaviour
- Abnormal dreams
- Adverse event
- Affect lability (emotional incontinence)
male:
n/a
What are the common side effects of Aviane-21, by age (0-1 to 60+) *:
0-1:
n/a
2-9:
n/a
10-19:
- Completed suicide (act of taking one's own life)
- Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dizziness
- Epistaxis (bleed from the nose)
- Metrorrhagia (uterine bleeding at irregular intervals)
20-29:
- Abdominal pain
- Abdominal distension
- Adverse event
- Aggression
- Alopecia (absence of hair from areas of the body)
- Anxiety
- Blood bilirubin increased
- Blood pressure decreased
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Depression
30-39:
- Malignant melanoma (skin cancer rises from melancytes)
- Dizziness
- Abnormal dreams
- Affect lability (emotional incontinence)
- Depression
- Dyspnoea (difficult or laboured respiration)
- Epistaxis (bleed from the nose)
- Muscle twitching
- Rash
40-49:
- Chest discomfort
- Dizziness
- Drug ineffective
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Dysgeusia (disorder of the sense of taste)
50-59:
- Carcinoid tumour pulmonary (slow growing tumour)
- Hypertension (high blood pressure)
- Pulmonary embolism (blockage of the main artery of the lung)
60+:
n/a
What are the common side effects of Aviane-21, by the time people have been on the drug (< 1 month to 10+ years)? *:
< 1 month:
- Affect lability (emotional incontinence)
- Back pain
- Blood pressure decreased
- Diarrhoea
- Dizziness
- Epistaxis (bleed from the nose)
1 - 6 months:
- Blood bilirubin increased
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Depression
- Drug ineffective
- Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
- Pulmonary embolism (blockage of the main artery of the lung)
6 - 12 months:
- Depression
- Hypertension (high blood pressure)
1 - 2 years:
n/a
2 - 5 years:
- Dyspareunia (painful sexual intercourse)
- Hypertension (high blood pressure)
5 - 10 years:
n/a
10+ years:
n/a
not specified:
- Malignant melanoma (skin cancer rises from melancytes)
- Abdominal pain
- Chest discomfort
- Blood glucose increased
- Dizziness
- Abdominal distension
- Carcinoid tumour pulmonary (slow growing tumour)
- Completed suicide (act of taking one's own life)
- Pulmonary embolism (blockage of the main artery of the lung)
- Abdominal pain upper
* Approximation only. Some reports may have incomplete information.
Do you take Aviane-21?
- Personalize this study to your gender and age- Predict drug outcomes for up to one year with AI
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How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
How the study uses the data?
The study is based on ethinyl estradiol; levonorgestrel (the active ingredients of Aviane-21) and Aviane-21 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.
Related studies are listed below in case you need more information:
Alternative drugs to, pros and cons of Aviane-21:
- Aviane-21 (99 reports)
All Aviane-21 side effects from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zWho is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
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