Chymotrypsin side effects, by duration, gender and age (a phase IV clinical study of FDA data)

female:

1. Overdose
2. Drug ineffective
3. Cerebral infarction (less blood supply to brain resulting tissue damage)
4. Visual field defect
5. Abdominal discomfort
6. Alanine aminotransferase increased
7. Arrhythmia (irregular heartbeat)
8. Blood glucose increased
9. Cough
10. Decreased appetite

male:

1. Basal ganglia haemorrhage (bleeding from blood vessels in an area of the brain responsible for body movements)
2. Abdominal pain
3. Multi-organ failure (multisystem organ failure)
4. Pneumonia
5. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
6. Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
7. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
8. Angioedema (rapid swelling of the dermis)
9. Antinuclear factor positive
10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

0-1:

1. Flushing (the warm, red condition of human skin)

2-9:

1. Epistaxis (bleed from the nose)

10-19:

1. Hepatic enzyme increased

20-29:

1. Drug ineffective
2. Abdominal pain

30-39:

1. Visual field defect
2. Abdominal discomfort
3. Angioedema (rapid swelling of the dermis)
4. Decreased appetite

40-49:

1. Abdominal pain
2. Bilirubin conjugated increased
3. Hypotension (abnormally low blood pressure)
4. Interstitial lung disease

50-59:

1. Atrial septal defect acquired (an abnormal opening between the left and right atria of the heart-acquired)
2. Alanine aminotransferase increased
3. Asthma
4. Blood albumin decreased
5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
6. Cold sweat
7. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
8. Hepatic enzyme increased
9. Hyperglycaemia (high blood sugar)
10. Lung adenocarcinoma (a form of non-small cell lung cancer)

60+:

1. Pneumonia
2. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
3. Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
4. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
5. Antinuclear factor positive
6. Arrhythmia (irregular heartbeat)
7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
8. Blood glucose increased
9. Blood pressure fluctuation
10. Cardiac failure chronic

< 1 month:

1. Overdose
2. Alanine aminotransferase increased
3. Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
4. Angioedema (rapid swelling of the dermis)
5. Arrhythmia (irregular heartbeat)
6. Bilirubin conjugated increased
7. Blood albumin decreased
8. Blood pressure fluctuation
9. Cold sweat
10. Dermatitis allergic (inflammation of the skin due allergic reaction)

1 - 6 months:

1. Decreased appetite

6 - 12 months:

n/a

1 - 2 years:

n/a

2 - 5 years:

n/a

5 - 10 years:

n/a

10+ years:

n/a

not specified:

1. Drug ineffective
2. Lymphadenopathy (disease or enlargement of lymph nodes)
3. Aortic thrombosis (formation of a blood clot inside aorta)
4. Cerebral infarction (less blood supply to brain resulting tissue damage)
5. Pneumonia
6. Abdominal discomfort
7. Abdominal pain
8. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
9. Adrenocortical insufficiency acute (suddenly adrenal glands do not produce adequate amounts of steroid hormones)
10. Antinuclear factor positive