Creatine side effects - from FDA reports


In this review, we analyze Creatine side effects by the time on the drug, gender and age of the people who have side effects while taking Creatine. The review is based on 256 people who have side effects while taking the drug from FDA, and is updated regularly.

Creatine

Creatine has active ingredients of creatine. It is often used in muscle mass. (latest outcomes from Creatine 370 users)


On May, 26, 2018

256 people who take Creatine are studied.


Number of reports submitted per year:

Creatine side effects.

Most common side effects over time *:

< 1 month:
  • White blood cell count decreased
  • Alanine aminotransferase increased
  • Cardiac death
  • White blood cell count increased
  • Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  • Platelet count decreased
  • Upper respiratory tract infection
  • Headache (pain in head)
  • Neutropenia (an abnormally low number of neutrophils)
  • Septic shock (shock due to blood infection)
1 - 6 months:
  • White blood cell count increased
6 - 12 months:
  • Limb injury
1 - 2 years:
  • Hypertension (high blood pressure)
not specified:
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Lactic acidosis (low ph in body tissues)
  • Suicidal ideation
  • Weight decreased
  • Pain in extremity
  • Weight increased
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Sinusitis (inflammation of sinus)
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Alanine aminotransferase increased

Most common side effects by gender *:

female:
  • Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  • Sinusitis (inflammation of sinus)
  • Vomiting
  • White blood cell count increased
  • Neutropenia (an abnormally low number of neutrophils)
  • Septic shock (shock due to blood infection)
  • Upper respiratory tract infection
  • Weight increased
  • White blood cell count decreased
  • Alanine aminotransferase increased
male:
  • White blood cell count increased
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Suicidal ideation
  • Lactic acidosis (low ph in body tissues)
  • Weight decreased
  • Pain in extremity
  • Alanine aminotransferase increased
  • Drug ineffective
  • Headache (pain in head)
  • Infection

Most common side effects by age *:

0-1:
  • Respiratory failure (inadequate gas exchange by the respiratory system)
2-9:
  • Drug ineffective
  • Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  • Infusion related reaction
  • Platelet count increased
10-19:
  • Infection
  • Osteomyelitis (infection of bone)
  • Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
  • Abdominal pain upper
  • Device related infection
  • Gastrointestinal viral infection (virus infection of gastrointestinal tract)
  • Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
  • Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  • Weight increased
20-29:
  • Aggression
  • Renal tubular necrosis (death of kidney tubules)
  • Upper respiratory tract infection
  • Depression
  • Gastritis (inflammation of stomach)
  • Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  • Hangover
  • Intervertebral disc protrusion (spinal disc protrusion)
  • Loss of libido (loss of sexual urge)
  • Mobility decreased (ability to move is reduced)
30-39:
  • White blood cell count increased
  • Alanine aminotransferase increased
  • Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  • Blood creatinine increased
  • Pain in extremity
  • Platelet count decreased
  • Sinusitis (inflammation of sinus)
  • Weight increased
  • Alopecia (absence of hair from areas of the body)
  • Arteriosclerosis (thickening and hardening of arteries)
40-49:
  • Lactic acidosis (low ph in body tissues)
  • Somnolence (a state of near-sleep, a strong desire for sleep)
  • Suicidal ideation
  • Renal failure acute (rapid kidney dysfunction)
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • White blood cell count decreased
  • White blood cell count increased
  • Accidental overdose
  • Acute hepatic failure
  • Axillary vein thrombosis (formation of a blood clot in axillary vein)
50-59:
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Weight increased
  • White blood cell count decreased
  • White blood cell count increased
  • Alanine aminotransferase increased
  • Back pain
  • Cardiotoxicity (damage to the heart muscle)
  • Dysuria (painful or difficult urination)
  • Haemorrhagic anaemia (anaemia due to excessive bleeding)
  • Headache (pain in head)
60+:
  • Neutropenia (an abnormally low number of neutrophils)
  • Pain in extremity
  • Septic shock (shock due to blood infection)
  • Vomiting
  • Weight decreased
  • Wheezing (a high-pitched whistling sound made while you breath)
  • Blood glucose abnormal
  • Cardiac death
  • Cardiac failure
  • Cerebral haemorrhage (bleeding within the brain)

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Subscribe to the study: get notified of updates to the study.

Do you have side effects when taking Creatine? Share you experience to help people like you.

Want to find out more about the FDA reports used in the study? You can request them from FDA.

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