Doxazosin mesylate side effects - from FDA reports


In this review, we analyze Doxazosin mesylate side effects by the time on the drug, gender and age of the people who have side effects while taking Doxazosin mesylate. The review is based on 8,558 people who have side effects while taking the drug from FDA, and is updated regularly.

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Doxazosin Mesylate

Doxazosin mesylate has active ingredients of doxazosin mesylate. It is often used in high blood pressure. (latest outcomes from Doxazosin mesylate 9,107 users)


On Jan, 10, 2019

8,558 people who take Doxazosin Mesylate are studied.


Number of reports submitted per year:

Doxazosin mesylate side effects.

Most common side effects over time *:

< 1 month:
  • Pyrexia (fever)
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • White blood cell count decreased
  • Anaphylactic reaction (serious allergic reaction)
  • Oedema peripheral (superficial swelling)
  • Renal infarct (kidney damage due to lack of blood supply)
  • Vomiting
  • White blood cell count increased
  • Abdominal distension
  • Lethargy (tiredness)
1 - 6 months:
  • Suicidal ideation
  • Cerebral infarction (less blood supply to brain resulting tissue damage)
  • Thrombocytopenia (decrease of platelets in blood)
  • Hallucination, visual (seeing things that aren't there)
  • Capillary leak syndrome (capillary leaks plasma)
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • Urinary incontinence (inability to control the flow of urine and involuntary urination)
  • Constipation
  • Depressed level of consciousness
  • Dyspnoea (difficult or laboured respiration)
6 - 12 months:
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Abdominal pain upper
  • Abortion spontaneous (naturally occurring miscarriage)
  • Blood pressure diastolic decreased
  • Hypokalaemia (low potassium)
  • Renal failure chronic (long lasting kidney dysfunction)
  • Stridor
  • Swollen tongue (swelling of tongue)
  • Visual impairment
  • Weight decreased
1 - 2 years:
  • Tooth loss
  • Anuria (failure of the kidneys to produce urine)
  • Death
  • Blood pressure decreased
  • Oedema (fluid collection in tissue)
  • Respiratory failure (inadequate gas exchange by the respiratory system)
  • Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  • Thalamus haemorrhage (bleeding in thalamus)
  • Vomiting
  • Weight decreased
2 - 5 years:
  • Renal failure acute (rapid kidney dysfunction)
  • Hypotension (abnormally low blood pressure)
  • Urinary incontinence (inability to control the flow of urine and involuntary urination)
  • Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  • Dizziness
  • Pancreatitis acute (sudden inflammation of pancreas)
  • Respiratory failure (inadequate gas exchange by the respiratory system)
  • Altered state of consciousness (altered state of mind)
  • Cerebral infarction (less blood supply to brain resulting tissue damage)
  • Colitis collagenous (inflammatory bowel disease affecting the colon)
5 - 10 years:
  • Neck pain
  • Renal failure acute (rapid kidney dysfunction)
  • Renal failure chronic (long lasting kidney dysfunction)
  • Renal impairment (severely reduced kidney function)
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
  • Acute myocardial infarction (acute heart attack)
  • Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
  • Blood lactic acid increased
  • Cerebral infarction (less blood supply to brain resulting tissue damage)
10+ years:
  • Erythema multiforme (a type of hypersensitivity reaction)
  • Sepsis (a severe blood infection that can lead to organ failure and death)
  • Colorectal cancer metastatic (cancer of colon and rectal spreads to other parts)
  • Fall
  • Thrombocytopenia (decrease of platelets in blood)
  • Toxic skin eruption (skin breakdown due to toxic substance)
  • Virus antibody test abnormal
not specified:
  • Vomiting
  • Weight decreased
  • Renal failure acute (rapid kidney dysfunction)
  • Drug ineffective
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • Weight increased
  • Renal failure (kidney dysfunction)
  • Death
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Rash

Most common side effects by gender *:

female:
  • Vomiting
  • Renal failure acute (rapid kidney dysfunction)
  • Dyspnoea (difficult or laboured respiration)
  • Weight decreased
  • White blood cell count decreased
  • Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  • Drug ineffective
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • Anaemia (lack of blood)
  • Renal failure (kidney dysfunction)
male:
  • Weight decreased
  • Vomiting
  • Pneumonia
  • White blood cell count decreased
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Nausea (feeling of having an urge to vomit)
  • Pyrexia (fever)
  • Pruritus (severe itching of the skin)
  • Vision blurred
  • Dyspnoea (difficult or laboured respiration)

Most common side effects by age *:

0-1:
  • Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  • Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  • Tremor (trembling or shaking movements in one or more parts of your body)
  • Ureteric cancer
2-9:
  • Fatigue (feeling of tiredness)
  • Accidental drug intake by child
  • Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  • Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  • Post procedural complication
  • Proteinuria present
  • Renal impairment (severely reduced kidney function)
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Spermatozoa progressive motility decreased
  • Syncope (loss of consciousness with an inability to maintain postural tone)
10-19:
  • Varicella
  • Anaphylactic reaction (serious allergic reaction)
  • Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
  • Arthralgia (joint pain)
  • B-cell lymphoma (blood cancer affecting b cells)
  • Growth hormone deficiency
  • Intentional overdose
  • Monoplegia (a paralysis of a single limb)
  • Pulmonary embolism (blockage of the main artery of the lung)
  • Reading disorder (problem in areas of the brain that help interpret language)
20-29:
  • Weight decreased
  • Blood glucose increased
  • Blood prolactin increased
  • Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  • Cholecystitis chronic (long lasting infection of gallbladder)
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Gait disturbance
  • Haemoglobin decreased
  • Pulmonary haemorrhage (acute bleeding from the lung)
  • Renal atrophy (wasting of kidney)
30-39:
  • Spermatozoa progressive motility decreased
  • Overdose
  • Spermatozoa progressive motility abnormal
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Conjunctivitis infective (infection of the conjunctiva)
  • Anaemia (lack of blood)
  • Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  • Pyrexia (fever)
  • White blood cell count increased
  • Anaphylactic reaction (serious allergic reaction)
40-49:
  • Vomiting
  • Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  • Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  • Urine output decreased
  • White blood cell count increased
  • Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  • Drug ineffective
  • Cerebral haemorrhage (bleeding within the brain)
  • Completed suicide (act of taking one's own life)
  • Gastric cancer stage iv (cancer cells have spread to distant organs)
50-59:
  • Vomiting
  • Weight decreased
  • Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  • Pneumonia
  • Pancreatitis acute (sudden inflammation of pancreas)
  • Weight increased
  • Drug ineffective
  • Renal failure acute (rapid kidney dysfunction)
  • Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  • Myalgia (muscle pain)
60+:
  • Vomiting
  • Renal failure acute (rapid kidney dysfunction)
  • Weight decreased
  • Syncope (loss of consciousness with an inability to maintain postural tone)
  • Death
  • White blood cell count decreased
  • Dyspnoea (difficult or laboured respiration)
  • Renal failure (kidney dysfunction)
  • Thrombocytopenia (decrease of platelets in blood)
  • Urinary tract infection

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

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On eHealthMe, Doxazosin mesylate (doxazosin mesylate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for and how effective they are.

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