Mexate side effects, by duration, gender and age (a phase IV clinical study of FDA data)
Summary:
Side effects are reported by people who take Mexate (methotrexate sodium). Common side effects include alanine aminotransferase increased among females and abscess intestinal among males.
The phase IV clinical study is created by eHealthMe based on 63 reports from the FDA, and is updated regularly.
What is Mexate?
Mexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 81 Mexate users. Check the latest studies of Mexate.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
63 people who take Mexate and have side effects are studied.

What are the common side effects of Mexate, by gender? *:
female:
- Alanine aminotransferase increased
- Abdominal pain upper
- Acne (skin problems that cause pimples)
- Fatigue (feeling of tiredness)
- Abnormal faeces (abnormal stool)
- Alveolitis fibrosing (idiopathic pulmonary fibrosis)
- Bone amp joint tuberculosis
- Cystitis haemorrhagic (blood in the urine and painful voiding)
- Drug hypersensitivity
- Drug maladministration
male:
- Abscess intestinal (collections of pus-intestinal)
- Biopsy lymph gland abnormal
- Surgery
- Blood creatinine decreased
- Blood culture positive
- Blood glucose increased
- Chest pain
- Dehydration (dryness resulting from the removal of water)
- Diabetes mellitus inadequate control
- Hodgkin's disease mixed cellularity recurrent (cancer originating from white blood cells)
What are the common side effects of Mexate, by age (0-1 to 60+) *:
0-1:
n/a
2-9:
- Alanine aminotransferase increased
10-19:
n/a
20-29:
- Blood culture positive
- Cystitis haemorrhagic (blood in the urine and painful voiding)
- Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
30-39:
- Alanine aminotransferase increased
- Abnormal faeces (abnormal stool)
- Injection site erythema (redness at injection site)
40-49:
- Abdominal pain upper
- Biopsy lymph gland abnormal
50-59:
- Bone amp joint tuberculosis
- Drug toxicity
- Gallbladder disorder
- Hodgkin's disease nodular sclerosis stage unspecified (cancer originating from white blood cells -unspecified)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Surgery
60+:
- Abscess intestinal (collections of pus-intestinal)
- Blood creatinine decreased
- Chest pain
- Drug hypersensitivity
- Hodgkin's disease mixed cellularity recurrent (cancer originating from white blood cells)
- Lentigo (a small pigmented spot on the skin with a clearly-defined edge, surrounded by normal-appearing skin)
What are the common side effects of Mexate, by the time people have been on the drug (< 1 month to 10+ years)? *:
< 1 month:
n/a
1 - 6 months:
n/a
6 - 12 months:
n/a
1 - 2 years:
n/a
2 - 5 years:
- Drug toxicity
5 - 10 years:
n/a
10+ years:
n/a
not specified:
- Alanine aminotransferase increased
- Blood culture positive
- Blood glucose increased
- Bone amp joint tuberculosis
- Chest pain
- Cystitis haemorrhagic (blood in the urine and painful voiding)
- Dehydration (dryness resulting from the removal of water)
- Diabetes mellitus inadequate control
- Drug hypersensitivity
- Drug maladministration
* Approximation only. Some reports may have incomplete information.
Do you take Mexate?
- Personalize this study to your gender and age- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
How the study uses the data?
The study is based on methotrexate sodium (the active ingredients of Mexate) and Mexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.
Related studies are listed below in case you need more information:
Alternative drugs to, pros and cons of Mexate:
- Mexate (81 reports)
All Mexate side effects from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zWho is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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