Trivora-28 side effects, by duration, gender and age (a phase IV clinical study of FDA data)

Summary:

Side effects are reported by people who take Trivora-28 (ethinyl estradiol; levonorgestrel). Common side effects include asthenia among females.

The phase IV clinical study is created by eHealthMe based on 56 reports from the FDA, and is updated regularly.

What is Trivora-28?

Trivora-28 has active ingredients of ethinyl estradiol; levonorgestrel. It is often used in birth control. eHealthMe is studying from 82 Trivora-28 users. Check the latest studies of Trivora-28.

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eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

56 people who take Trivora-28 and have side effects are studied.

Trivora-28 side effects.

What are the common side effects of Trivora-28, by gender? *:

female:

  1. Asthenia (weakness)
  2. Asthma
  3. Bacterial infection
  4. Balance disorder
  5. Blood pressure increased
  6. Breast tenderness
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Conjunctivitis (pink eye)
  10. Depressed level of consciousness

male:

n/a

What are the common side effects of Trivora-28, by age (0-1 to 60+) *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Sinusitis (inflammation of sinus)

20-29:

  1. Asthma
  2. Activities of daily living impaired
  3. Asthenia (weakness)
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Conjunctivitis (pink eye)
  6. Infectious mononucleosis (infection usually caused by the epstein-barr virus)
  7. Injection site erythema (redness at injection site)
  8. Menstruation irregular
  9. Metrorrhagia (uterine bleeding at irregular intervals)

30-39:

  1. Drug ineffective
  2. Asthenia (weakness)
  3. Breast tenderness
  4. Focal nodular hyperplasia (tumour of the liver)
  5. Gastric disorder (disease of stomach)
  6. Hospitalisation
  7. Injection site pain
  8. Palpitations (feelings or sensations that your heart is pounding or racing)

40-49:

  1. Cough
  2. Fungal infection
  3. Abdominal distension
  4. Blood pressure increased
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Depressed level of consciousness
  7. Dysgeusia (disorder of the sense of taste)
  8. Endometrial hypertrophy (enlargement of uterine wall from the increase in size of its cells)
  9. Erythema (redness of the skin)
  10. Fall

50-59:

n/a

60+:

n/a

What are the common side effects of Trivora-28, by the time people have been on the drug (< 1 month to 10+ years)? *:

< 1 month:

  1. Asthenia (weakness)
  2. Breast tenderness
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Conjunctivitis (pink eye)
  5. Influenza like illness

1 - 6 months:

  1. Palpitations (feelings or sensations that your heart is pounding or racing)

6 - 12 months:

  1. Depressed level of consciousness

1 - 2 years:

  1. Balance disorder
  2. Endometrial hypertrophy (enlargement of uterine wall from the increase in size of its cells)

2 - 5 years:

  1. Depression

5 - 10 years:

n/a

10+ years:

n/a

not specified:

  1. Appetite disorder (abnormal eating habits)
  2. Asthma
  3. Cough
  4. Drug ineffective
  5. Fungal infection
  6. Sinusitis (inflammation of sinus)
  7. Abdominal distension
  8. Activities of daily living impaired
  9. Asthenia (weakness)
  10. Bacterial infection

* Approximation only. Some reports may have incomplete information.

Do you take Trivora-28?

- Personalize this study to your gender and age
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How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.



How the study uses the data?

The study is based on ethinyl estradiol; levonorgestrel (the active ingredients of Trivora-28) and Trivora-28 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

Related studies are listed below in case you need more information:

Alternative drugs to, pros and cons of Trivora-28:

All Trivora-28 side effects from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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