Abitrexate and Pulmonary embolism - a phase IV clinical study of FDA data

Summary:

Pulmonary embolism is reported as a side effect among people who take Abitrexate (methotrexate sodium), especially for people who are female, 60+ old, also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Pulmonary embolism when taking Abitrexate. It is created by eHealthMe based on reports of 27 people who have side effects when taking Abitrexate from the FDA, and is updated regularly.

What is Abitrexate?

Abitrexate has active ingredients of methotrexate sodium. eHealthMe is studying from 35 Abitrexate users. Check the latest studies of Abitrexate.

What is Pulmonary embolism?

Pulmonary embolism (blockage of the main artery of the lung) is found to be associated with 2,334 drugs and 2,959 conditions by eHealthMe. Check the latest studies of Pulmonary embolism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

27 people reported to have side effects when taking Abitrexate.
Among them, 11 people (40.74%) have Pulmonary embolism.

Could Abitrexate cause Pulmonary embolism?

Among these 11 people:

What is the gender of people who have Pulmonary embolism when taking Abitrexate? *

female: 100 %
male: 0.0 %

What is the age of people who have Pulmonary embolism when taking Abitrexate? *

What are other drugs people take besides Abitrexate? *

Enbrel: 9 people, 81.82%
Xarelto: 2 people, 18.18%
Lyrica: 2 people, 18.18%
Humira: 2 people, 18.18%

What are other side effects people have besides Pulmonary embolism? *

Sinusitis (inflammation of sinus): 9 people, 81.82%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 81.82%
Upper Respiratory Tract Infection: 5 people, 45.45%
Lower Respiratory Tract Infection: 2 people, 18.18%
Fainting (loss of consciousness and postural tone): 2 people, 18.18%
C-Reactive Protein Increased: 2 people, 18.18%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 72.73%

* Approximation only. Some reports may have incomplete information.

Do you take Abitrexate and have Pulmonary embolism?

- Check whether Pulmonary embolism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Abitrexate:

Abitrexate (35 reports)

Browse all side effects of Abitrexate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pulmonary embolism:

Pulmonary embolism (2,334 drugs)

Browse all the conditions that are associated with Pulmonary embolism:

Pulmonary embolism (2,959 conditions)

Related publications that referenced our studies

Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on methotrexate sodium (the active ingredients of Abitrexate) and Abitrexate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.