Accupril and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Accupril (quinapril hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Vioxx, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Accupril. It is created by eHealthMe based on reports of 13,164 people who have side effects when taking Accupril from the FDA, and is updated regularly.

What is Accupril?

Accupril has active ingredients of quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,404 Accupril users. Check the latest studies of Accupril.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 685 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jul, 05, 2026

13,164 people reported to have side effects when taking Accupril.
Among them, 17 people (0.13%) have Diastolic dysfunction.

Could Accupril cause Diastolic dysfunction?

Among these 17 people:

How long have people been on Accupril when they have Diastolic dysfunction? *

What is the gender of people who have Diastolic dysfunction when taking Accupril? *

female: 50 %
male: 50 %

What is the age of people who have Diastolic dysfunction when taking Accupril? *

What are other drugs people take besides Accupril? *

What are other side effects people have besides Diastolic dysfunction? *

Coronary Heart Disease (narrowing or blockage of the coronary arteries): 11 people, 64.71%
Tricuspid Valve Incompetence (inefficient heart valve): 9 people, 52.94%
Chest Pain: 8 people, 47.06%
Mitral Valve Incompetence (inefficient heart valve): 8 people, 47.06%
Cardiac Failure Congestive: 7 people, 41.18%
Pain: 7 people, 41.18%
Heart Attack: 7 people, 41.18%
Osteoporosis (bones weak and more likely to break): 6 people, 35.29%
Depression: 6 people, 35.29%
Cataract (clouding of the lens inside the eye): 6 people, 35.29%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 23.53%
High Blood Cholesterol: 3 people, 17.65%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 17.65%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 3 people, 17.65%
Diabetes: 3 people, 17.65%
Multiple Myeloma (cancer of the plasma cells): 3 people, 17.65%
Ventricular Dysfunction (heart dysfunction): 1 person, 5.88%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.88%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.88%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Accupril and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Accupril:

Accupril (13,404 reports)

Browse all side effects of Accupril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (685 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on quinapril hydrochloride (the active ingredients of Accupril) and Accupril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.