Acephen and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Acephen (acetaminophen), especially for people who are male, 60+ old, also take Morphine, and have Gastroesophageal reflux disease.

The study is created by eHealthMe based on reports of 85 people who have side effects when taking Acephen from the FDA, and is updated regularly.

What is Acephen?

Acephen has active ingredients of acetaminophen. eHealthMe is studying from 91 Acephen users. Check the latest studies of Acephen.

On Jul, 08, 2026

85 people reported to have side effects when taking Acephen.
Among them, 13 people (15.29%) died.

Among these 13 people:

What is the gender of people who died when taking Acephen? *

female: 41.67 %
male: 58.33 %

What is the age of people who died when taking Acephen? *

What are other drugs people take besides Acephen? *

What are other side effects people have before they died? *

Acute Kidney Failure: 2 people, 15.38%
Gastric Cancer (stomach cancer): 2 people, 15.38%
Chronic Kidney Disease: 2 people, 15.38%
Renal Injury (kidney injury): 2 people, 15.38%
Signet-Ring Cell Carcinoma (signet cell cancer tumour): 2 people, 15.38%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 7.69%
Hepatic Lesion: 1 person, 7.69%
Dizziness: 1 person, 7.69%
Drowsiness: 1 person, 7.69%
Drug Hypersensitivity: 1 person, 7.69%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Prostate Cancer: 2 people, 15.38%
Parkinson's Disease: 2 people, 15.38%
Breast Cancer: 2 people, 15.38%
Renal Cell Carcinoma (a kidney cancer): 1 person, 7.69%
Neoplasm Malignant (cancer tumour): 1 person, 7.69%
Muscle Spasms (muscle contraction): 1 person, 7.69%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
Metastases To Bone (cancer spreads to bone): 1 person, 7.69%
Constipation: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acephen:

Acephen (91 reports)

Expand to all the drugs that have ingredients of acetaminophen:

Death and drugs with ingredients of acetaminophen (13,376 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acephen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,141 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen (the active ingredients of Acephen) and Acephen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.