Acetaminophen and hydrocodone bitartrate and Multiple sclerosis - a phase IV clinical study of FDA data

Summary:

Multiple sclerosis is reported as a side effect among people who take Acetaminophen and hydrocodone bitartrate (acetaminophen; hydrocodone bitartrate), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Baclofen, and have Depression.

The phase IV clinical study analyzes which people have Multiple sclerosis when taking Acetaminophen and hydrocodone bitartrate. It is created by eHealthMe based on reports of 5,944 people who have side effects when taking Acetaminophen and hydrocodone bitartrate from the FDA, and is updated regularly.

What is Acetaminophen and hydrocodone bitartrate?

Acetaminophen and hydrocodone bitartrate has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 6,101 Acetaminophen and hydrocodone bitartrate users. Check the latest studies of Acetaminophen and hydrocodone bitartrate.

What is Multiple sclerosis?

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) is found to be associated with 1,084 drugs and 1,366 conditions by eHealthMe. Check the latest studies of Multiple sclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

5,944 people reported to have side effects when taking Acetaminophen and hydrocodone bitartrate.
Among them, 24 people (0.4%) have Multiple sclerosis.

Could Acetaminophen and hydrocodone bitartrate cause Multiple sclerosis?

Among these 24 people:

How long have people been on Acetaminophen and hydrocodone bitartrate when they have Multiple sclerosis? *

What is the gender of people who have Multiple sclerosis when taking Acetaminophen and hydrocodone bitartrate? *

female: 100 %
male: 0.0 %

What is the age of people who have Multiple sclerosis when taking Acetaminophen and hydrocodone bitartrate? *

What are other drugs people take besides Acetaminophen and hydrocodone bitartrate? *

What are other side effects people have besides Multiple sclerosis? *

Weakness: 14 people, 58.33%
Cachexia (loss of weight): 12 people, 50.00%
Fall: 12 people, 50.00%
Pneumonia: 11 people, 45.83%
Drug Ineffective: 10 people, 41.67%
Stress And Anxiety: 9 people, 37.50%
Memory Loss: 9 people, 37.50%
Hypotension (abnormally low blood pressure): 8 people, 33.33%
Depression: 8 people, 33.33%
Joint Pain: 7 people, 29.17%

What are the existing conditions these people have? *

Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 10 people, 41.67%
Depression: 10 people, 41.67%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 7 people, 29.17%
Neuralgia (pain in one or more nerves): 7 people, 29.17%
Indigestion: 7 people, 29.17%
Fatigue (feeling of tiredness): 7 people, 29.17%
Breast Cancer Metastatic: 6 people, 25.00%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 8.33%
Diabetes: 2 people, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and hydrocodone bitartrate and have Multiple sclerosis?

- Check whether Multiple sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen and hydrocodone bitartrate:

Acetaminophen and hydrocodone bitartrate (6,101 reports)

Multiple sclerosis treatments and more:

Multiple sclerosis (799,637 reports)

How severe was Multiple sclerosis and when was it recovered:

Multiple sclerosis in Acetaminophen and hydrocodone bitartrate

Expand to all the drugs that have ingredients of acetaminophen; hydrocodone bitartrate:

Multiple sclerosis and drugs with ingredients of acetaminophen; hydrocodone bitartrate (842 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and hydrocodone bitartrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple sclerosis:

Multiple sclerosis (1,084 drugs)

Browse all the conditions that are associated with Multiple sclerosis:

Multiple sclerosis (1,366 conditions)

Related publications that referenced our studies

Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate (the active ingredients of Acetaminophen and hydrocodone bitartrate) and Acetaminophen and hydrocodone bitartrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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