Acetylcysteine and Hypoaesthesia - a phase IV clinical study of FDA data


Hypoaesthesia is found among people who take Acetylcysteine, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Acetylcysteine and have Hypoaesthesia. It is created by eHealthMe based on reports of 8,033 people who have side effects when taking Acetylcysteine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On May, 22, 2022

8,033 people reported to have side effects when taking Acetylcysteine.
Among them, 50 people (0.62%) have Hypoaesthesia.

What is Acetylcysteine?

Acetylcysteine has active ingredients of acetylcysteine. It is often used in cough. eHealthMe is studying from 8,116 Acetylcysteine users for its effectiveness, alternative drugs and more.

What is Hypoaesthesia?

Hypoaesthesia (reduced sense of touch or sensation) is found to be associated with 3,356 drugs and 3,091 conditions by eHealthMe.

Number of Acetylcysteine and Hypoaesthesia reports submitted per year:

Could Acetylcysteine cause Hypoaesthesia?

Time on Acetylcysteine when people have Hypoaesthesia *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hypoaesthesia when taking Acetylcysteine *:

  • female: 61.22 %
  • male: 38.78 %

Age of people who have Hypoaesthesia when taking Acetylcysteine *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.88 %
  • 20-29: 2.44 %
  • 30-39: 9.76 %
  • 40-49: 7.32 %
  • 50-59: 29.27 %
  • 60+: 46.34 %

Common drugs people take besides Acetylcysteine *:

  1. Pantoprazole: 9 people, 18.00%
  2. Albuterol: 6 people, 12.00%
  3. Omeprazole: 6 people, 12.00%
  4. Diclofenac: 6 people, 12.00%
  5. Colace: 6 people, 12.00%
  6. Acetaminophen: 5 people, 10.00%
  7. Atrovent: 5 people, 10.00%
  8. Lyrica: 5 people, 10.00%
  9. Lasix: 5 people, 10.00%
  10. Ipratropium Bromide: 5 people, 10.00%

Common side effects people have besides Hypoaesthesia *:

  1. Fatigue (feeling of tiredness): 22 people, 44.00%
  2. Nausea (feeling of having an urge to vomit): 21 people, 42.00%
  3. Weakness: 17 people, 34.00%
  4. Tremor (trembling or shaking movements in one or more parts of your body): 17 people, 34.00%
  5. Pain In Extremity: 17 people, 34.00%
  6. Diarrhea: 16 people, 32.00%
  7. Joint Pain: 15 people, 30.00%
  8. Nausea And Vomiting: 15 people, 30.00%
  9. Pain: 15 people, 30.00%
  10. Dizziness: 14 people, 28.00%

Common conditions people have *:

  1. Pain: 9 people, 18.00%
  2. High Blood Pressure: 6 people, 12.00%
  3. Wheezing (a high-pitched whistling sound made while you breath): 5 people, 10.00%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 8.00%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 8.00%
  6. Myosclerosis (hardening of muscle tissue): 4 people, 8.00%
  7. Fever: 4 people, 8.00%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.00%
  9. Diarrhea: 4 people, 8.00%
  10. Thyroid Diseases: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Acetylcysteine and have Hypoaesthesia?

Check whether Hypoaesthesia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Acetylcysteine:

Hypoaesthesia treatments and more:

COVID vaccines that are related to Hypoaesthesia:

How severe was Hypoaesthesia and when was it recovered:

Expand to all the drugs that have ingredients of acetylcysteine:

Common drugs associated with Hypoaesthesia:

All the drugs that are associated with Hypoaesthesia:

Common conditions associated with Hypoaesthesia:

All the conditions that are associated with Hypoaesthesia:

How the study uses the data?

The study uses data from the FDA. It is based on acetylcysteine (the active ingredients of Acetylcysteine) and Acetylcysteine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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