Acetylcysteine and Tibia fracture - a phase IV clinical study of FDA data

Summary:

Tibia fracture is reported as a side effect among people who take Acetylcysteine (acetylcysteine), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Flexeril, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Tibia fracture when taking Acetylcysteine. It is created by eHealthMe based on reports of 11,475 people who have side effects when taking Acetylcysteine from the FDA, and is updated regularly.

What is Acetylcysteine?

Acetylcysteine has active ingredients of acetylcysteine. It is often used in cough. eHealthMe is studying from 11,563 Acetylcysteine users. Check the latest studies of Acetylcysteine.

What is Tibia fracture?

Tibia fracture (fracture of lower leg bone) is found to be associated with 643 drugs and 670 conditions by eHealthMe. Check the latest studies of Tibia fracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

11,475 people reported to have side effects when taking Acetylcysteine.
Among them, 20 people (0.17%) have Tibia fracture.

$Could Acetylcysteine cause Tibia fracture?$

Among these 20 people:

How long have people been on Acetylcysteine when they have Tibia fracture? *

What is the gender of people who have Tibia fracture when taking Acetylcysteine? *

female: 100 %
male: 0.0 %

What is the age of people who have Tibia fracture when taking Acetylcysteine? *

What are other drugs people take besides Acetylcysteine? *

What are other side effects people have besides Tibia fracture? *

Stress And Anxiety: 20 people, 100.00%
Emotional Distress: 19 people, 95.00%
Pain: 19 people, 95.00%
Compression Fracture (fracture due to pressure caused by injury): 18 people, 90.00%
Blood Immunoglobulin G Decreased: 17 people, 85.00%
Bone Deformity: 17 people, 85.00%
Loss Of Consciousness: 17 people, 85.00%
Loose Tooth: 17 people, 85.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 17 people, 85.00%
High Blood Pressure: 17 people, 85.00%

What are the existing conditions these people have? *

Bone Disorder: 6 people, 30.00%
Multiple Myeloma (cancer of the plasma cells): 6 people, 30.00%
Pain: 3 people, 15.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
Viral Infection: 2 people, 10.00%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 10.00%
Bacterial Infection: 2 people, 10.00%
Diabetes: 2 people, 10.00%
High Blood Cholesterol: 2 people, 10.00%
Hiv Infection: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Acetylcysteine and have Tibia fracture?

- Check whether Tibia fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetylcysteine:

Acetylcysteine (11,563 reports)

Tibia fracture treatments and more:

Tibia fracture (6,376 reports)

Browse all side effects of Acetylcysteine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tibia fracture:

Tibia fracture (643 drugs)

Browse all the conditions that are associated with Tibia fracture:

Tibia fracture (670 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetylcysteine (the active ingredients of Acetylcysteine) and Acetylcysteine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.