Aciphex and Ear buzzing - a phase IV clinical study of FDA data

Summary:

Ear buzzing is reported as a side effect among people who take Aciphex (rabeprazole sodium), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Prilosec, and have Depression.

The phase IV clinical study analyzes which people have Ear buzzing when taking Aciphex. It is created by eHealthMe based on reports of 24,594 people who have side effects when taking Aciphex from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

What is Ear buzzing?

Ear buzzing is found to be associated with 2,401 drugs and 3,082 conditions by eHealthMe. Check the latest studies of Ear buzzing.

On Nov, 28, 2025

24,594 people reported to have side effects when taking Aciphex.
Among them, 132 people (0.54%) have Ear buzzing.

Among these 132 people:

* Approximation only. Some reports may have incomplete information.

Do you take Aciphex and have Ear buzzing?

- Check whether Ear buzzing is associated with a drug or a condition (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aciphex:

Aciphex (25,301 reports)

Ear buzzing treatments and more:

Ear buzzing (58,542 reports)

How severe was Ear buzzing and when was it recovered:

Ear buzzing in Aciphex

Expand to all the drugs that have ingredients of rabeprazole sodium:

Ear buzzing and drugs with ingredients of rabeprazole sodium (230 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Aciphex side effects:

Browse all side effects of Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ear buzzing:

Browse all the drugs that are associated with Ear buzzing:

Ear buzzing (2,401 drugs)

Common conditions associated with Ear buzzing:

Depression aggravated: 3,635 reports
Antidepressant therapy: 3,623 reports
Hypertension: 2,663 reports
Hbp: 2,652 reports
Ra: 1,927 reports
Anxiety aggravated: 1,913 reports
Stress: 1,912 reports
Pain: 1,795 reports
Alternative medicine - pain relief: 1,778 reports
Blood cholesterol abnormal: 1,671 reports

Browse all the conditions that are associated with Ear buzzing:

Ear buzzing (3,082 conditions)

Drugs similar to Aciphex and Ear buzzing :

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Aciphex) and Aciphex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.