Aciphex and Localised oedema - a phase IV clinical study of FDA data

Summary:

Localised oedema is reported as a side effect among people who take Aciphex (rabeprazole sodium), especially for people who are female, 40-49 old, also take Synthroid, and have Asthma.

The phase IV clinical study analyzes which people have Localised oedema when taking Aciphex. It is created by eHealthMe based on reports of 24,594 people who have side effects when taking Aciphex from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

What is Localised oedema?

Localised oedema (fluid retention in a particular part of the body) is found to be associated with 552 drugs and 707 conditions by eHealthMe. Check the latest studies of Localised oedema.

On Jul, 05, 2026

24,594 people reported to have side effects when taking Aciphex.
Among them, 27 people (0.11%) have Localised oedema.

Among these 27 people:

What is the gender of people who have Localised oedema when taking Aciphex? *

female: 100 %
male: 0.0 %

What is the age of people who have Localised oedema when taking Aciphex? *

What are other drugs people take besides Aciphex? *

What are other side effects people have besides Localised oedema? *

Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 15 people, 55.56%
Hepatic Steatosis (fatty liver disease): 15 people, 55.56%
Cholecystitis Chronic (long lasting infection of gallbladder): 15 people, 55.56%
Gallbladder Cholesterolosis (accumulation and deposition of cholesterol inside of the): 14 people, 51.85%
Muscle Spasms (muscle contraction): 11 people, 40.74%
Dizziness: 10 people, 37.04%
Hepatic Neoplasm (liver tumour): 10 people, 37.04%
Pain: 10 people, 37.04%
Arrhythmias (irregular heartbeat): 10 people, 37.04%
Dyspnea (difficult or laboured breathing): 9 people, 33.33%

What are the existing conditions these people have? *

Asthma: 14 people, 51.85%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 33.33%
Cough: 9 people, 33.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 22.22%
Oedema (fluid collection in tissue): 4 people, 14.81%
Insomnia (sleeplessness): 1 person, 3.70%
Cardiac Disorder: 1 person, 3.70%
Cardiac Failure: 1 person, 3.70%
Constipation: 1 person, 3.70%
Drug Hypersensitivity: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Aciphex and have Localised oedema?

- Check whether Localised oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aciphex:

Aciphex (25,301 reports)

Browse all side effects of Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Localised oedema:

Localised oedema (552 drugs)

Browse all the conditions that are associated with Localised oedema:

Localised oedema (707 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Aciphex) and Aciphex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.