Aciphex and Uc - a phase IV clinical study of FDA data

Summary:

Uc is reported as a side effect among people who take Aciphex (rabeprazole sodium), especially for people who are female, 60+ old, also take Accutane, and have Acne.

The phase IV clinical study analyzes which people have Uc when taking Aciphex. It is created by eHealthMe based on reports of 24,594 people who have side effects when taking Aciphex from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,300 Aciphex users. Check the latest studies of Aciphex.

What is Uc?

Uc is found to be associated with 1,327 drugs and 2,013 conditions by eHealthMe. Check the latest studies of Uc.

On Sep, 26, 2025

24,594 people reported to have side effects when taking Aciphex.
Among them, 49 people (0.2%) have Uc.

Among these 49 people:

What is the gender of people who have Uc when taking Aciphex? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Uc when taking Aciphex? *

What are other drugs people take besides Aciphex? *

What are other side effects people have besides Uc? *

Stress And Anxiety: 24 people, 48.98%
Inflammatory Bowel Disease: 19 people, 38.78%
Fatigue (feeling of tiredness): 16 people, 32.65%
Colitis (inflammation of colon): 16 people, 32.65%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 15 people, 30.61%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 15 people, 30.61%
Suicidal Ideation: 15 people, 30.61%
Itching: 14 people, 28.57%
Rotator Cuff Syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 13 people, 26.53%
Insomnia (sleeplessness): 13 people, 26.53%

What are the existing conditions these people have? *

Acne (skin problems that cause pimples): 19 people, 38.78%
Back Pain: 14 people, 28.57%
Gastric Ulcer (stomach ulcer): 14 people, 28.57%
Irritable Bowel Syndrome: 5 people, 10.20%
High Blood Pressure: 5 people, 10.20%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 8.16%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 8.16%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 6.12%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.08%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 4.08%

* Approximation only. Some reports may have incomplete information.

Do you take Aciphex and have Uc?

- Check whether Uc is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Aciphex:

Aciphex (25,300 reports)

Uc treatments and more:

Uc (188,229 reports)

Browse all side effects of Aciphex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Uc:

Uc (1,327 drugs)

Browse all the conditions that are associated with Uc:

Uc (2,013 conditions)

Drugs similar to Aciphex and Uc :

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Aciphex) and Aciphex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.