Actemra and Herpes simplex aggravated - a phase IV clinical study of FDA data

Summary:

Herpes simplex aggravated is reported as a side effect among people who take Actemra (tocilizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Arthritis.

The phase IV clinical study analyzes which people have Herpes simplex aggravated when taking Actemra. It is created by eHealthMe based on reports of 102,551 people who have side effects when taking Actemra from the FDA, and is updated regularly.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.

What is Herpes simplex aggravated?

Herpes simplex aggravated (serious herpes simplex is a common viral infection) is found to be associated with 704 drugs and 290 conditions by eHealthMe. Check the latest studies of Herpes simplex aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

102,551 people reported to have side effects when taking Actemra.
Among them, 15 people (0.01%) have Herpes simplex aggravated.

Could Actemra cause Herpes simplex aggravated?

Among these 15 people:

How long have people been on Actemra when they have Herpes simplex aggravated? *

What is the gender of people who have Herpes simplex aggravated when taking Actemra? *

female: 92.31 %
male: 7.69 %

What is the age of people who have Herpes simplex aggravated when taking Actemra? *

What are other drugs people take besides Actemra? *

Methotrexate: 6 people, 40.00%
Calcium: 4 people, 26.67%
Acyclovir: 3 people, 20.00%
Levothyroxine Sodium: 3 people, 20.00%
Folic Acid: 3 people, 20.00%
Tylenol: 3 people, 20.00%
Methylprednisolone Sodium Succinate: 3 people, 20.00%
Benadryl: 3 people, 20.00%
Colace: 3 people, 20.00%
Prednisolone: 3 people, 20.00%

What are other side effects people have besides Herpes simplex aggravated? *

Bone Density Decreased: 4 people, 26.67%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 20.00%
Lichen Planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash): 3 people, 20.00%
Cataract (clouding of the lens inside the eye): 3 people, 20.00%
Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 13.33%
Death: 2 people, 13.33%
Cushingoid (obesity and weakening of the muscles): 2 people, 13.33%
Myopathy (a muscular disease in which the muscle fibres do not function): 2 people, 13.33%
Corneal Dystrophy (abnormal deposition of substances in the transparent front part of the eye): 2 people, 13.33%
Lung Neoplasm (tumour of lung): 2 people, 13.33%

What are the existing conditions these people have? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 13.33%
Swelling: 2 people, 13.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Hyperhidrosis (abnormally increased sweating): 2 people, 13.33%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 13.33%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 1 person, 6.67%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 1 person, 6.67%
Impaired Gastric Emptying: 1 person, 6.67%
Oral Herpes (viral infection of mouth): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Actemra and have Herpes simplex aggravated?

- Check whether Herpes simplex aggravated is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actemra:

Actemra (102,759 reports)

Browse all side effects of Actemra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herpes simplex aggravated:

Herpes simplex aggravated (704 drugs)

Browse all the conditions that are associated with Herpes simplex aggravated:

Herpes simplex aggravated (290 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tocilizumab (the active ingredients of Actemra) and Actemra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.