Actemra and Peritonitis - a phase IV clinical study of FDA data

Summary:

Peritonitis is reported as a side effect among people who take Actemra (tocilizumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prednisolone, and have Osteoporosis.

The phase IV clinical study analyzes which people have Peritonitis when taking Actemra. It is created by eHealthMe based on reports of 102,551 people who have side effects when taking Actemra from the FDA, and is updated regularly.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.

What is Peritonitis?

Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs) is found to be associated with 1,050 drugs and 1,576 conditions by eHealthMe. Check the latest studies of Peritonitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

102,551 people reported to have side effects when taking Actemra.
Among them, 93 people (0.09%) have Peritonitis.

Among these 93 people:

How long have people been on Actemra when they have Peritonitis? *

What is the gender of people who have Peritonitis when taking Actemra? *

female: 58.7 %
male: 41.3 %

What is the age of people who have Peritonitis when taking Actemra? *

What are other drugs people take besides Actemra? *

What are other side effects people have besides Peritonitis? *

Large Intestine Perforation (hole in large intestine): 15 people, 16.13%
Gastrointestinal Perforation (hole in the digestive tract): 15 people, 16.13%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 15 people, 16.13%
Diverticular Perforation (serious gastrointestinal condition in which the intestine's walls are perforated): 9 people, 9.68%
Fever: 8 people, 8.60%
Cardiac Failure: 8 people, 8.60%
Thrombocytopenia (decrease of platelets in blood): 8 people, 8.60%
Septic Shock (shock due to blood infection): 7 people, 7.53%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 6 people, 6.45%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 6.45%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 7 people, 7.53%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 6 people, 6.45%
High Blood Pressure: 4 people, 4.30%
Rectal Cancer Recurrent (reoccurrence of rectum cancer): 3 people, 3.23%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 3.23%
Constipation: 3 people, 3.23%
Rectal Cancer (cancer of rectum): 3 people, 3.23%
Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 3 people, 3.23%
Nausea (feeling of having an urge to vomit): 2 people, 2.15%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 2 people, 2.15%

* Approximation only. Some reports may have incomplete information.

Do you take Actemra and have Peritonitis?

- Check whether Peritonitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actemra:

Actemra (102,759 reports)

Peritonitis treatments and more:

Peritonitis (27,277 reports)

Browse all side effects of Actemra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peritonitis:

Peritonitis (1,050 drugs)

Browse all the conditions that are associated with Peritonitis:

Peritonitis (1,576 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tocilizumab (the active ingredients of Actemra) and Actemra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.