Actemra and Ventricular fibrillation - a phase IV clinical study of FDA data

Summary:

Ventricular fibrillation is reported as a side effect among people who take Actemra (tocilizumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Prednisolone, and have Burkitt lymphoma.

The phase IV clinical study analyzes which people have Ventricular fibrillation when taking Actemra. It is created by eHealthMe based on reports of 102,551 people who have side effects when taking Actemra from the FDA, and is updated regularly.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.

What is Ventricular fibrillation?

Ventricular fibrillation (abnormally irregular heart rhythm) is found to be associated with 1,092 drugs and 1,246 conditions by eHealthMe. Check the latest studies of Ventricular fibrillation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

102,551 people reported to have side effects when taking Actemra.
Among them, 13 people (0.01%) have Ventricular fibrillation.

Could Actemra cause Ventricular fibrillation?

Among these 13 people:

How long have people been on Actemra when they have Ventricular fibrillation? *

What is the gender of people who have Ventricular fibrillation when taking Actemra? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Ventricular fibrillation when taking Actemra? *

What are other drugs people take besides Actemra? *

Prednisolone: 3 people, 23.08%
Vancomycin: 1 person, 7.69%
Simvastatin: 1 person, 7.69%
Renagel: 1 person, 7.69%
Plavix: 1 person, 7.69%
Piperacillin And Tazobactam: 1 person, 7.69%
Micardis: 1 person, 7.69%
Methotrexate: 1 person, 7.69%
Leflunomide: 1 person, 7.69%
Lasix: 1 person, 7.69%

What are other side effects people have besides Ventricular fibrillation? *

Cardiac Arrest: 3 people, 23.08%
Infusion Related Reaction: 2 people, 15.38%
White Blood Cell Count Increased: 1 person, 7.69%
Diarrhea: 1 person, 7.69%
Heart Attack: 1 person, 7.69%
Fever: 1 person, 7.69%
Felty's Syndrome (a combination of rheumatoid arthritis, an enlarged spleen, an abnormally low white blood count): 1 person, 7.69%
Fall: 1 person, 7.69%
Fainting (loss of consciousness and postural tone): 1 person, 7.69%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 1 person, 7.69%

What are the existing conditions these people have? *

Itching: 1 person, 7.69%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Diabetes: 1 person, 7.69%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 1 person, 7.69%
Chronic Renal Failure (kidney failure): 1 person, 7.69%
Castleman's Disease (a disease of lymph nodes and related tissues): 1 person, 7.69%
Burkitt Lymphoma (cancer of the lymphatic system): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Actemra and have Ventricular fibrillation?

- Check whether Ventricular fibrillation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actemra:

Actemra (102,759 reports)

Browse all side effects of Actemra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular fibrillation:

Ventricular fibrillation (1,092 drugs)

Browse all the conditions that are associated with Ventricular fibrillation:

Ventricular fibrillation (1,246 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tocilizumab (the active ingredients of Actemra) and Actemra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.