Acth and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Acth (corticotropin), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Ampyra, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Sciatica when taking Acth. It is created by eHealthMe based on reports of 5,384 people who have side effects when taking Acth from the FDA, and is updated regularly.

What is Acth?

Acth has active ingredients of corticotropin. eHealthMe is studying from 5,402 Acth users. Check the latest studies of Acth.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,145 drugs and 1,429 conditions by eHealthMe. Check the latest studies of Sciatica.



On Apr, 02, 2026

5,384 people reported to have side effects when taking Acth.
Among them, 10 people (0.19%) have Sciatica.

Could Acth cause Sciatica?

Among these 10 people:

How long have people been on Acth when they have Sciatica? *

  • < 1 month: 20 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 60 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sciatica when taking Acth? *

  • female: 70 %
  • male: 30 %

What is the age of people who have Sciatica when taking Acth? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 50.0 %
  • 60+: 37.5 %

What are other drugs people take besides Acth? *

  1. Solu-Medrol: 2 people, 20.00%
  2. Percocet: 2 people, 20.00%
  3. Osphena: 2 people, 20.00%
  4. Diflucan: 2 people, 20.00%
  5. Benadryl: 2 people, 20.00%
  6. Ampyra: 2 people, 20.00%
  7. Zinbryta: 1 person, 10.00%
  8. Xiidra: 1 person, 10.00%
  9. Vivelle-Dot: 1 person, 10.00%
  10. Valium: 1 person, 10.00%

What are other side effects people have besides Sciatica? *

  1. Weight Decreased: 5 people, 50.00%
  2. Itching: 5 people, 50.00%
  3. Rashes (redness): 4 people, 40.00%
  4. Joint Swelling: 4 people, 40.00%
  5. Dry Mouth: 4 people, 40.00%
  6. Hypotension (abnormally low blood pressure): 3 people, 30.00%
  7. Injection Site Discoloration: 3 people, 30.00%
  8. Fungal Infection: 3 people, 30.00%
  9. Joint Pain: 3 people, 30.00%
  10. Foot Deformity (functional disability of foot): 3 people, 30.00%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 50.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 40.00%
  3. Osteoporosis (bones weak and more likely to break): 2 people, 20.00%
  4. Optic Neuritis (optic nerve inflammation): 2 people, 20.00%
  5. Itching: 2 people, 20.00%
  6. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 10.00%
  7. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 10.00%
  8. Intervertebral Disc Protrusion (spinal disc protrusion): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Acth and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acth:

  • Acth (5,402 reports)

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of corticotropin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acth:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:


How the study uses the data?

The study uses data from the FDA. It is based on corticotropin (the active ingredients of Acth) and Acth (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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