Actifed and Peptic ulcer aggravated - a phase IV clinical study of FDA data

Summary:

Peptic ulcer aggravated is reported as a side effect among people who take Actifed (pseudoephedrine hydrochloride; triprolidine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Effexor, and have Osteoarthritis.

The phase IV clinical study analyzes which people have Peptic ulcer aggravated when taking Actifed. It is created by eHealthMe based on reports of 991 people who have side effects when taking Actifed from the FDA, and is updated regularly.

What is Actifed?

Actifed has active ingredients of pseudoephedrine hydrochloride; triprolidine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,091 Actifed users. Check the latest studies of Actifed.

What is Peptic ulcer aggravated?

Peptic ulcer aggravated is found to be associated with 1,491 drugs and 545 conditions by eHealthMe. Check the latest studies of Peptic ulcer aggravated.

On Jul, 17, 2026

991 people reported to have side effects when taking Actifed.
Among them, 15 people (1.51%) have Peptic ulcer aggravated.

Could Actifed cause Peptic ulcer aggravated?

Among these 15 people:

How long have people been on Actifed when they have Peptic ulcer aggravated? *

What is the gender of people who have Peptic ulcer aggravated when taking Actifed? *

female: 13.33 %
male: 86.67 %

What is the age of people who have Peptic ulcer aggravated when taking Actifed? *

What are other drugs people take besides Actifed? *

What are other side effects people have besides Peptic ulcer aggravated? *

Anaemia (lack of blood): 10 people, 66.67%
Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 9 people, 60.00%
Melaena (the passage of black, tarry stools): 7 people, 46.67%
Pain In Extremity: 3 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 20.00%
Vaginal Bleeding: 2 people, 13.33%
Gums - Swollen: 2 people, 13.33%
General Physical Health Deterioration (weak health status): 2 people, 13.33%
Gingival Erythema (redness of gums): 2 people, 13.33%
Gingival Ulceration (ulcer on gums): 2 people, 13.33%

What are the existing conditions these people have? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 66.67%
Nasopharyngitis (inflammation of the nasopharynx): 9 people, 60.00%
Hot Flush (sudden feelings of heat): 2 people, 13.33%
Breast Cancer: 2 people, 13.33%
Hepatitis C: 1 person, 6.67%
Allergic Rhinitis: 1 person, 6.67%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 6.67%
Colitis (inflammation of colon): 1 person, 6.67%
Diarrhea: 1 person, 6.67%
Enlarged Prostate: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Actifed and have Peptic ulcer aggravated?

- Check whether Peptic ulcer aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actifed:

Actifed (1,091 reports)

Peptic ulcer aggravated treatments and more:

Peptic ulcer aggravated (42 reports)

How severe was Peptic ulcer aggravated and when was it recovered:

Peptic ulcer aggravated in Actifed

Expand to all the drugs that have ingredients of pseudoephedrine hydrochloride; triprolidine hydrochloride:

Peptic ulcer aggravated and drugs with ingredients of pseudoephedrine hydrochloride; triprolidine hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actifed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (1,491 drugs)

Browse all the conditions that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (545 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pseudoephedrine hydrochloride; triprolidine hydrochloride (the active ingredients of Actifed) and Actifed (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.