Actiq and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Actiq (fentanyl citrate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Duragesic-100, and have Pancreatitis.

The phase IV clinical study analyzes which people have Coma when taking Actiq. It is created by eHealthMe based on reports of 27,560 people who have side effects when taking Actiq from the FDA, and is updated regularly.

What is Actiq?

Actiq has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 27,583 Actiq users. Check the latest studies of Actiq.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,821 drugs and 3,206 conditions by eHealthMe. Check the latest studies of Coma.

On Apr, 09, 2026

27,560 people reported to have side effects when taking Actiq.
Among them, 40 people (0.15%) have Coma.

Among these 40 people:

How long have people been on Actiq when they have Coma? *

What is the gender of people who have Coma when taking Actiq? *

female: 47.5 %
male: 52.5 %

What is the age of people who have Coma when taking Actiq? *

What are other drugs people take besides Actiq? *

What are other side effects people have besides Coma? *

Pneumonia: 4 people, 10.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 10.00%
Drug Toxicity: 4 people, 10.00%
Multi-Organ Failure (multisystem organ failure): 4 people, 10.00%
Memory Loss: 4 people, 10.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 10.00%
Overdose: 4 people, 10.00%
Suicide Attempt: 4 people, 10.00%
Depression: 4 people, 10.00%
Nausea And Vomiting: 3 people, 7.50%

What are the existing conditions these people have? *

Pancreatitis (inflammation of pancreas): 6 people, 15.00%
Diabetes: 4 people, 10.00%
Neck Pain: 3 people, 7.50%
Back Pain: 3 people, 7.50%
Platelet Aggregation Inhibition: 2 people, 5.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.00%
Pain In Extremity: 1 person, 2.50%
Muscle Atrophy (a decrease in the mass of the muscle): 1 person, 2.50%
Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 1 person, 2.50%
Insomnia (sleeplessness): 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Actiq and have Coma?

- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actiq:

Actiq (27,583 reports)

Coma treatments and more:

Coma (57,420 reports)

Browse all side effects of Actiq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Coma:

Coma (2,821 drugs)

Browse all the conditions that are associated with Coma:

Coma (3,206 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Actiq) and Actiq (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.