Activase and Extrasystoles - a phase IV clinical study of FDA data

Summary:

Extrasystoles is reported as a side effect among people who take Activase (alteplase), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Heparin, and have Acute myocardial infarction.

The phase IV clinical study analyzes which people have Extrasystoles when taking Activase. It is created by eHealthMe based on reports of 7,505 people who have side effects when taking Activase from the FDA, and is updated regularly.

What is Activase?

Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.

What is Extrasystoles?

Extrasystoles is found to be associated with 744 drugs and 952 conditions by eHealthMe. Check the latest studies of Extrasystoles.

On Jul, 11, 2026

7,505 people reported to have side effects when taking Activase.
Among them, 53 people (0.71%) have Extrasystoles.

Among these 53 people:

How long have people been on Activase when they have Extrasystoles? *

What is the gender of people who have Extrasystoles when taking Activase? *

female: 15.38 %
male: 84.62 %

What is the age of people who have Extrasystoles when taking Activase? *

What are other drugs people take besides Activase? *

What are other side effects people have besides Extrasystoles? *

Chest Pain: 24 people, 45.28%
Ventricular Extrasystoles (premature cardiac contraction): 14 people, 26.42%
Nausea (feeling of having an urge to vomit): 11 people, 20.75%
Hypotension (abnormally low blood pressure): 11 people, 20.75%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 10 people, 18.87%
Nausea And Vomiting: 9 people, 16.98%
Arrhythmias (irregular heartbeat): 8 people, 15.09%
Electrocardiogram St Segment Elevation: 5 people, 9.43%
Atelectasis (partial or complete collapse of the lung): 5 people, 9.43%
Fatigue (feeling of tiredness): 5 people, 9.43%

What are the existing conditions these people have? *

Acute Myocardial Infarction (acute heart attack): 33 people, 62.26%
Heart Attack: 9 people, 16.98%
Pneumonia: 2 people, 3.77%
Pericarditis (inflammation of the pericardium): 2 people, 3.77%
Urinary Tract Infection: 1 person, 1.89%
Sedation: 1 person, 1.89%
Neuropathy Peripheral (surface nerve damage): 1 person, 1.89%
Mood Swings (an extreme or rapid change in mood): 1 person, 1.89%
Infection: 1 person, 1.89%
High Blood Pressure: 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Activase and have Extrasystoles?

- Check whether Extrasystoles is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Activase:

Activase (7,526 reports)

Extrasystoles treatments and more:

Extrasystoles (8,909 reports)

Browse all side effects of Activase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extrasystoles:

Extrasystoles (743 drugs)

Browse all the conditions that are associated with Extrasystoles:

Extrasystoles (952 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alteplase (the active ingredients of Activase) and Activase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.