Activase and Head injury - a phase IV clinical study of FDA data

Summary:

Head injury is reported as a side effect among people who take Activase (alteplase), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Heparin, and have Metastases to bone.

The phase IV clinical study analyzes which people have Head injury when taking Activase. It is created by eHealthMe based on reports of 7,505 people who have side effects when taking Activase from the FDA, and is updated regularly.

What is Activase?

Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.

What is Head injury?

Head injury is found to be associated with 2,628 drugs and 3,247 conditions by eHealthMe. Check the latest studies of Head injury.

On Jul, 11, 2026

7,505 people reported to have side effects when taking Activase.
Among them, 35 people (0.47%) have Head injury.

Among these 35 people:

How long have people been on Activase when they have Head injury? *

What is the gender of people who have Head injury when taking Activase? *

female: 67.74 %
male: 32.26 %

What is the age of people who have Head injury when taking Activase? *

What are other drugs people take besides Activase? *

What are other side effects people have besides Head injury? *

Pain: 13 people, 37.14%
Headache (pain in head): 13 people, 37.14%
Joint Pain: 12 people, 34.29%
Diarrhea: 12 people, 34.29%
Rashes (redness): 10 people, 28.57%
Fever: 9 people, 25.71%
Fall: 9 people, 25.71%
Neuropathy Peripheral (surface nerve damage): 9 people, 25.71%
Chest Pain: 9 people, 25.71%
Dehydration (dryness resulting from the removal of water): 8 people, 22.86%

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 11.43%
Metastases To Bone (cancer spreads to bone): 4 people, 11.43%
Acute Myocardial Infarction (acute heart attack): 3 people, 8.57%
Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 8.57%
Immunodeficiency: 3 people, 8.57%
Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 3 people, 8.57%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 5.71%
Epstein-Barr Virus Infection: 2 people, 5.71%
Heart Attack: 2 people, 5.71%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Activase and have Head injury?

- Check whether Head injury is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Activase:

Activase (7,526 reports)

Head injury treatments and more:

Head injury (160,560 reports)

Browse all side effects of Activase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Head injury:

Head injury (2,628 drugs)

Browse all the conditions that are associated with Head injury:

Head injury (3,247 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alteplase (the active ingredients of Activase) and Activase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.