Activase and Menopause - a phase IV clinical study of FDA data

Summary:

Menopause is reported as a side effect among people who take Activase (alteplase), especially for people who are 50-59 old, also take Ditropan Xl, and have Bone density abnormal.

The phase IV clinical study analyzes which people have Menopause when taking Activase. It is created by eHealthMe based on reports of 7,505 people who have side effects when taking Activase from the FDA, and is updated regularly.

What is Activase?

Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.

What is Menopause?

Menopause (end of monthly cycles in women) is found to be associated with 399 drugs and 488 conditions by eHealthMe. Check the latest studies of Menopause.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

7,505 people reported to have side effects when taking Activase.
Among them, 14 people (0.19%) have Menopause.

Among these 14 people:

What is the age of people who have Menopause when taking Activase? *

What are other drugs people take besides Activase? *

What are other side effects people have besides Menopause? *

Wound Infection Staphylococcal: 14 people, 100.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 14 people, 100.00%
Neuropathy Peripheral (surface nerve damage): 14 people, 100.00%
Mastication Disorder (disease of chewing food): 14 people, 100.00%
Bronchopleural Fistula: 14 people, 100.00%
Lung Neoplasm Malignant (cancer tumour of lung): 14 people, 100.00%
Lung Infection: 14 people, 100.00%
Lip Discoloration: 14 people, 100.00%
Lip And/or Oral Cavity Cancer (cancer of lip or mouth): 14 people, 100.00%
Cerebrovascular Disorder (disease of brain): 14 people, 100.00%

What are the existing conditions these people have? *

Bone Density Abnormal: 14 people, 100.00%
Osteoporosis (bones weak and more likely to break): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

Do you take Activase and have Menopause?

- Check whether Menopause is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Activase:

Activase (7,526 reports)

Menopause treatments and more:

Menopause (14,552 reports)

Browse all side effects of Activase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Menopause:

Menopause (399 drugs)

Browse all the conditions that are associated with Menopause:

Menopause (488 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alteplase (the active ingredients of Activase) and Activase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.