Activase and Shock - a phase IV clinical study of FDA data

Summary:

Shock is reported as a side effect among people who take Activase (alteplase), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Versed, and have Cerebral infarction.

The phase IV clinical study analyzes which people have Shock when taking Activase. It is created by eHealthMe based on reports of 7,505 people who have side effects when taking Activase from the FDA, and is updated regularly.

What is Activase?

Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.

What is Shock?

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin) is found to be associated with 1,226 drugs and 1,753 conditions by eHealthMe. Check the latest studies of Shock.

On May, 04, 2026

7,505 people reported to have side effects when taking Activase.
Among them, 19 people (0.25%) have Shock.

Among these 19 people:

How long have people been on Activase when they have Shock? *

What is the gender of people who have Shock when taking Activase? *

female: 52.63 %
male: 47.37 %

What is the age of people who have Shock when taking Activase? *

What are other drugs people take besides Activase? *

Acetaminophen: 2 people, 10.53%
Nitroglycerin: 2 people, 10.53%
Lasix: 2 people, 10.53%
Diprivan: 2 people, 10.53%
Demerol: 2 people, 10.53%
Morphine Sulfate: 2 people, 10.53%
Bisacodyl: 2 people, 10.53%
Albuterol: 2 people, 10.53%
Versed: 2 people, 10.53%
Amoxicillin And Clavulanate Potassium: 1 person, 5.26%

What are other side effects people have besides Shock? *

Hypotension (abnormally low blood pressure): 6 people, 31.58%
Acute Kidney Failure: 4 people, 21.05%
Cardiac Arrest: 4 people, 21.05%
Cardiac Failure Congestive: 3 people, 15.79%
Ventricular Fibrillation (abnormally irregular heart rhythm): 3 people, 15.79%
Lactic Acidosis (low ph in body tissues): 3 people, 15.79%
Haemodynamic Instability (disturbances in the blood movement in our body): 3 people, 15.79%
Anaemia (lack of blood): 3 people, 15.79%
Arrhythmias (irregular heartbeat): 3 people, 15.79%
Pulmonary Oedema (fluid accumulation in the lungs): 3 people, 15.79%

What are the existing conditions these people have? *

Heart Attack: 4 people, 21.05%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 4 people, 21.05%
Sedation: 2 people, 10.53%
Thrombolysis (resolving the blood clot): 1 person, 5.26%
Cerebral Artery Embolism (sudden blocking of an artery by a clot or foreign material): 1 person, 5.26%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.26%
Embolic Stroke (stroke due to obstruction due to an embolus): 1 person, 5.26%
General Anaesthesia: 1 person, 5.26%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 5.26%
High Blood Pressure: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Activase and have Shock?

- Check whether Shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Activase:

Activase (7,526 reports)

Shock treatments and more:

Shock (28,534 reports)

Browse all side effects of Activase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Shock:

Shock (1,226 drugs)

Browse all the conditions that are associated with Shock:

Shock (1,753 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on alteplase (the active ingredients of Activase) and Activase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.