Actonel with calcium and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Actonel with calcium (calcium carbonate; risedronate sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Actonel, and have Osteoporosis.

The phase IV clinical study analyzes which people have Pain when taking Actonel with calcium. It is created by eHealthMe based on reports of 104 people who have side effects when taking Actonel with calcium from the FDA, and is updated regularly.

What is Actonel with calcium?

Actonel with calcium has active ingredients of calcium carbonate; risedronate sodium. eHealthMe is studying from 124 Actonel with calcium users. Check the latest studies of Actonel with calcium.

What is Pain?

Pain is found to be associated with 3,816 drugs and 5,866 conditions by eHealthMe. Check the latest studies of Pain.

On Jul, 17, 2026

104 people reported to have side effects when taking Actonel with calcium.
Among them, 13 people (12.5%) have Pain.

Among these 13 people:

How long have people been on Actonel with calcium when they have Pain? *

What is the gender of people who have Pain when taking Actonel with calcium? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Pain when taking Actonel with calcium? *

What are other drugs people take besides Actonel with calcium? *

Actonel: 7 people, 53.85%
Fosamax: 6 people, 46.15%
Prilosec: 6 people, 46.15%
Caduet: 5 people, 38.46%
Sulfamethoxazole And Trimethoprim: 5 people, 38.46%
Forteo: 5 people, 38.46%
Fish Oil: 5 people, 38.46%
Meloxicam: 5 people, 38.46%
Detrol La: 5 people, 38.46%
Nystatin: 5 people, 38.46%

What are other side effects people have besides Pain? *

Pathological Fracture (broken bone caused by disease): 7 people, 53.85%
Broken Bone: 7 people, 53.85%
Pain In Extremity: 7 people, 53.85%
Joint Pain: 6 people, 46.15%
Gait Disturbance: 6 people, 46.15%
Femur Fracture: 6 people, 46.15%
Muscle Atrophy (a decrease in the mass of the muscle): 5 people, 38.46%
Groin Pain: 5 people, 38.46%
Tenderness (pain or discomfort when an affected area is touched): 5 people, 38.46%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 5 people, 38.46%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 7 people, 53.85%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 3 people, 23.08%
High Blood Pressure: 3 people, 23.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 23.08%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 3 people, 23.08%
Constipation: 3 people, 23.08%
Back Pain: 3 people, 23.08%
Atrophic Vulvovaginitis (inflammation of the vulva): 3 people, 23.08%
Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 15.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel with calcium and have Pain?

- Check whether Pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel with calcium:

Actonel with calcium (124 reports)

Pain treatments and more:

Pain (1,140,594 reports)

How severe was Pain and when was it recovered:

Pain in Actonel with calcium

Expand to all the drugs that have ingredients of calcium carbonate; risedronate sodium:

Pain and drugs with ingredients of calcium carbonate; risedronate sodium

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actonel with calcium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

Pain (3,816 drugs)

Browse all the conditions that are associated with Pain:

Pain (5,866 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on calcium carbonate; risedronate sodium (the active ingredients of Actonel with calcium) and Actonel with calcium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.