Actonel and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Fosamax, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Cachexia when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 735 drugs and 1,194 conditions by eHealthMe. Check the latest studies of Cachexia.

On Aug, 01, 2025

28,929 people reported to have side effects when taking Actonel.
Among them, 21 people (0.07%) have Cachexia.

Among these 21 people:

How long have people been on Actonel when they have Cachexia? *

What is the gender of people who have Cachexia when taking Actonel? *

female: 100 %
male: 0.0 %

What is the age of people who have Cachexia when taking Actonel? *

What are other drugs people take besides Actonel? *

Fosamax: 11 people, 52.38%
Acetaminophen And Hydrocodone Bitartrate: 7 people, 33.33%
Baclofen: 7 people, 33.33%
Torsemide: 7 people, 33.33%
Cyclobenzaprine Hydrochloride: 7 people, 33.33%
Methotrexate: 4 people, 19.05%
Levaquin: 3 people, 14.29%
Rocaltrol: 3 people, 14.29%
Albuterol: 3 people, 14.29%
Alendronate Sodium: 3 people, 14.29%

What are other side effects people have besides Cachexia? *

Fall: 11 people, 52.38%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 10 people, 47.62%
Headache (pain in head): 10 people, 47.62%
Back Pain: 10 people, 47.62%
Ligament Sprain (ligament stretched): 10 people, 47.62%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 42.86%
Occipital Neuralgia (a condition characterized by chronic pain in the upper neck): 9 people, 42.86%
Excoriation (to tear or wear off the skin of): 9 people, 42.86%
Broken Bone: 9 people, 42.86%
Joint Dislocation (a joint position is changed from normal position): 8 people, 38.10%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 19.05%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 14.29%
Hepatitis (inflammation of the liver): 3 people, 14.29%
Oedema (fluid collection in tissue): 1 person, 4.76%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.76%
Joint Pain: 1 person, 4.76%
Inflammatory Bowel Disease: 1 person, 4.76%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 4.76%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel:

Actonel (29,369 reports)

Cachexia treatments and more:

Cachexia (7,763 reports)

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Cachexia (735 drugs)

Browse all the conditions that are associated with Cachexia:

Cachexia (1,194 conditions)

Drugs similar to Actonel and Cachexia :

Related publications that referenced our studies

Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.