Actonel and Cdf/cdf - a phase IV clinical study of FDA data

Summary:

Cdf/cdf is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Fosamax, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Cdf/cdf when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Cdf/cdf?

Cdf/cdf is found to be associated with 1,884 drugs and 1,775 conditions by eHealthMe. Check the latest studies of Cdf/cdf.



On Mar, 31, 2026

28,929 people reported to have side effects when taking Actonel.
Among them, 63 people (0.22%) have Cdf/cdf.

Could Actonel cause Cdf/cdf?

Among these 63 people:

How long have people been on Actonel when they have Cdf/cdf? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 40 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 10 %
  • 10+ years: 0.0 %

What is the gender of people who have Cdf/cdf when taking Actonel? *

  • female: 90.16 %
  • male: 9.84 %

What is the age of people who have Cdf/cdf when taking Actonel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 12.24 %
  • 50-59: 24.49 %
  • 60+: 48.98 %

What are other drugs people take besides Actonel? *

  1. Fosamax: 21 people, 33.33%
  2. Boniva: 10 people, 15.87%
  3. Calcium: 9 people, 14.29%
  4. Prednisone: 8 people, 12.70%
  5. Lipitor: 7 people, 11.11%
  6. Humira: 6 people, 9.52%
  7. Zocor: 6 people, 9.52%
  8. Alendronate Sodium: 5 people, 7.94%
  9. Vitamin D3: 5 people, 7.94%
  10. Evista: 5 people, 7.94%

What are other side effects people have besides Cdf/cdf? *

  1. Depression: 22 people, 34.92%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 19 people, 30.16%
  3. Diarrhea: 19 people, 30.16%
  4. Hypotension (abnormally low blood pressure): 18 people, 28.57%
  5. Joint Pain: 15 people, 23.81%
  6. Tooth Disorder (tooth disease): 15 people, 23.81%
  7. Femur Fracture: 15 people, 23.81%
  8. Urinary Tract Infection: 14 people, 22.22%
  9. Back Pain: 14 people, 22.22%
  10. Stress And Anxiety: 14 people, 22.22%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 22.22%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9 people, 14.29%
  3. High Blood Pressure: 8 people, 12.70%
  4. Indigestion: 4 people, 6.35%
  5. Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 6.35%
  6. Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 4.76%
  7. Depression: 3 people, 4.76%
  8. Diabetes: 3 people, 4.76%
  9. High Blood Cholesterol: 3 people, 4.76%
  10. Gastric Ulcer (stomach ulcer): 2 people, 3.17%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Cdf/cdf?

- Check whether Cdf/cdf is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel:

Cdf/cdf treatments and more:

How severe was Cdf/cdf and when was it recovered:

Expand to all the drugs that have ingredients of risedronate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cdf/cdf:

Browse all the conditions that are associated with Cdf/cdf:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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