Actonel and Coughing - a phase IV clinical study of FDA data

Summary:

Coughing is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Coughing when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Coughing?

Coughing is found to be associated with 3,179 drugs and 3,778 conditions by eHealthMe. Check the latest studies of Coughing.



On Dec, 16, 2025

28,929 people reported to have side effects when taking Actonel.
Among them, 1,296 people (4.48%) have Coughing.

Could Actonel cause Coughing?

Among these 1,296 people:

How long have people been on Actonel when they have Coughing? *

  • < 1 month: 8.55 %
  • 1 - 6 months: 20.51 %
  • 6 - 12 months: 8.55 %
  • 1 - 2 years: 17.09 %
  • 2 - 5 years: 32.48 %
  • 5 - 10 years: 11.11 %
  • 10+ years: 1.71 %

What is the gender of people who have Coughing when taking Actonel? *

  • female: 84.27 %
  • male: 15.73 %

What is the age of people who have Coughing when taking Actonel? *

  • 0-1: 0.0 %
  • 2-9: 0.09 %
  • 10-19: 0.37 %
  • 20-29: 0.09 %
  • 30-39: 4.08 %
  • 40-49: 9.45 %
  • 50-59: 20.02 %
  • 60+: 65.89 %

What are other drugs people take besides Actonel? *

  1. Prednisone: 229 people, 17.67%
  2. Fosamax: 227 people, 17.52%
  3. Ventolin: 191 people, 14.74%
  4. Synthroid: 160 people, 12.35%
  5. Calcium: 145 people, 11.19%
  6. Lipitor: 135 people, 10.42%
  7. Rituxan: 133 people, 10.26%
  8. Celebrex: 132 people, 10.19%
  9. Singulair: 131 people, 10.11%
  10. Aspirin: 126 people, 9.72%

What are other side effects people have besides Coughing? *

  1. Dyspnea (difficult or laboured breathing): 515 people, 39.74%
  2. Chest Pain: 352 people, 27.16%
  3. High Blood Pressure: 340 people, 26.23%
  4. Pain: 339 people, 26.16%
  5. Joint Pain: 305 people, 23.53%
  6. Nasopharyngitis (inflammation of the nasopharynx): 287 people, 22.15%
  7. Oedema Peripheral (superficial swelling): 277 people, 21.37%
  8. Sinusitis (inflammation of sinus): 271 people, 20.91%
  9. Fatigue (feeling of tiredness): 264 people, 20.37%
  10. Asthma: 262 people, 20.22%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 359 people, 27.70%
  2. Asthma: 167 people, 12.89%
  3. High Blood Pressure: 159 people, 12.27%
  4. Seasonal Allergy (allergic condition due to certain season): 116 people, 8.95%
  5. High Blood Cholesterol: 70 people, 5.40%
  6. Pain: 62 people, 4.78%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 51 people, 3.94%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 43 people, 3.32%
  9. Depression: 42 people, 3.24%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 37 people, 2.85%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Coughing?

- Check whether Coughing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel:

Coughing treatments and more:

How severe was Coughing and when was it recovered:

Expand to all the drugs that have ingredients of risedronate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Actonel side effects:

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Coughing:

Browse all the drugs that are associated with Coughing:

Common conditions associated with Coughing:

Browse all the conditions that are associated with Coughing:

Drugs similar to Actonel and Coughing :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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