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Actonel and Hepatic neoplasm - a phase IV clinical study of FDA data

Summary:

Hepatic neoplasm is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Vitamin D, and have Carcinoid tumor.

The phase IV clinical study analyzes which people have Hepatic neoplasm when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Hepatic neoplasm?

Hepatic neoplasm (liver tumour) is found to be associated with 489 drugs and 519 conditions by eHealthMe. Check the latest studies of Hepatic neoplasm.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

28,929 people reported to have side effects when taking Actonel.
Among them, 26 people (0.09%) have Hepatic neoplasm.

Could Actonel cause Hepatic neoplasm?

Among these 26 people:

How long have people been on Actonel when they have Hepatic neoplasm? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 66.67 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hepatic neoplasm when taking Actonel? *

  • female: 30.77 %
  • male: 69.23 %

What is the age of people who have Hepatic neoplasm when taking Actonel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.85 %
  • 40-49: 0.0 %
  • 50-59: 19.23 %
  • 60+: 76.92 %

What are other drugs people take besides Actonel? *

  1. Calcium: 16 people, 61.54%
  2. Sandostatin: 16 people, 61.54%
  3. Vitamin D: 16 people, 61.54%
  4. Plavix: 15 people, 57.69%
  5. Ativan: 15 people, 57.69%
  6. Nexium: 15 people, 57.69%
  7. Magnesium: 15 people, 57.69%
  8. Lipitor: 15 people, 57.69%
  9. Combigan: 15 people, 57.69%
  10. Dexilant: 15 people, 57.69%

What are other side effects people have besides Hepatic neoplasm? *

  1. Nausea (feeling of having an urge to vomit): 19 people, 73.08%
  2. Diarrhea: 17 people, 65.38%
  3. Nausea And Vomiting: 17 people, 65.38%
  4. Headache (pain in head): 17 people, 65.38%
  5. Back Pain: 17 people, 65.38%
  6. Joint Pain: 17 people, 65.38%
  7. Pain In Extremity: 17 people, 65.38%
  8. Pain: 17 people, 65.38%
  9. General Physical Health Deterioration (weak health status): 16 people, 61.54%
  10. Malaise (a feeling of general discomfort or uneasiness): 16 people, 61.54%

What are the existing conditions these people have? *

  1. Carcinoid Tumor: 15 people, 57.69%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 15.38%
  3. Neuroendocrine Tumor: 4 people, 15.38%
  4. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 3.85%
  5. Polychondritis (progressive inflammation of cartilage and other connective tissue): 1 person, 3.85%
  6. Irritable Bowel Syndrome: 1 person, 3.85%
  7. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 3.85%
  8. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 3.85%
  9. High Blood Pressure: 1 person, 3.85%
  10. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Hepatic neoplasm?

- Check whether Hepatic neoplasm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel:

Hepatic neoplasm treatments and more:

How severe was Hepatic neoplasm and when was it recovered:

Expand to all the drugs that have ingredients of risedronate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic neoplasm:

Browse all the conditions that are associated with Hepatic neoplasm:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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