Actonel and Hypercalcaemia - a phase IV clinical study of FDA data
Summary:
Hypercalcaemia is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Humira, and have Rheumatoid arthritis.
The phase IV clinical study analyzes which people have Hypercalcaemia when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.
What is Actonel?
Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.
What is Hypercalcaemia?
Hypercalcaemia (elevated calcium (ca+) level in the blood) is found to be associated with 1,103 drugs and 1,013 conditions by eHealthMe. Check the latest studies of Hypercalcaemia.
28,929 people reported to have side effects when taking Actonel.
Among them, 194 people (0.67%) have Hypercalcaemia.

Among these 194 people:
How long have people been on Actonel when they have Hypercalcaemia? *
What is the gender of people who have Hypercalcaemia when taking Actonel? *
What is the age of people who have Hypercalcaemia when taking Actonel? *
What are other drugs people take besides Actonel? *
What are other side effects people have besides Hypercalcaemia? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Actonel and have Hypercalcaemia?
- Check whether Hypercalcaemia is associated with a drug or a condition (FREE)
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Related studies:
Effectiveness of, long term effects of, and alternative drugs to Actonel:
- Actonel (29,369 reports)
Hypercalcaemia treatments and more:
- Hypercalcaemia (18,731 reports)
How severe was Hypercalcaemia and when was it recovered:
Expand to all the drugs that have ingredients of risedronate sodium:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Actonel side effects:
- Actonel side effect: Fall (2,644 reports)
- Actonel side effect: Drug ineffective (2,541 reports)
- Actonel side effect: Diarrhea (2,211 reports)
- Actonel side effect: High blood pressure (2,169 reports)
Browse all side effects of Actonel:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Hypercalcaemia:
- Prednisone side effect: Hypercalcaemia (1,865 reports)
- Methotrexate side effect: Hypercalcaemia (1,560 reports)
- Humira side effect: Hypercalcaemia (1,189 reports)
- Fosamax side effect: Hypercalcaemia (1,150 reports)
- Enbrel side effect: Hypercalcaemia (1,148 reports)
- Leflunomide side effect: Hypercalcaemia (1,118 reports)
- Remicade side effect: Hypercalcaemia (1,114 reports)
- Sulfasalazine side effect: Hypercalcaemia (1,106 reports)
- Orencia side effect: Hypercalcaemia (1,094 reports)
- Codeine side effect: Hypercalcaemia (1,073 reports)
Browse all the drugs that are associated with Hypercalcaemia:
- Hypercalcaemia (1,103 drugs)
Common conditions associated with Hypercalcaemia:
- Myeloma - multiple: 1,531 reports
- Ra: 1,418 reports
- Osteoporosis: 1,322 reports
- Thin bones: 1,275 reports
- Hypertension: 1,010 reports
- Blood pressure increased: 1,000 reports
- Pain: 563 reports
- Psoriasis: 457 reports
- Psoriatic arthropathy: 420 reports
- Breast cancer: 299 reports
Browse all the conditions that are associated with Hypercalcaemia:
- Hypercalcaemia (1,013 conditions)
Drugs similar to Actonel and Hypercalcaemia :
Related publications that referenced our studies
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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