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Actonel and Increased upper airway secretion - a phase IV clinical study of FDA data

Summary:

Increased upper airway secretion is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Norvasc, and have Gastric mucosal hypertrophy.

The phase IV clinical study analyzes which people have Increased upper airway secretion when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Increased upper airway secretion?

Increased upper airway secretion is found to be associated with 614 drugs and 627 conditions by eHealthMe. Check the latest studies of Increased upper airway secretion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

28,929 people reported to have side effects when taking Actonel.
Among them, 37 people (0.13%) have Increased upper airway secretion.

Could Actonel cause Increased upper airway secretion?

Among these 37 people:

How long have people been on Actonel when they have Increased upper airway secretion? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Increased upper airway secretion when taking Actonel? *

  • female: 94.44 %
  • male: 5.56 %

What is the age of people who have Increased upper airway secretion when taking Actonel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 3.23 %
  • 60+: 96.77 %

What are other drugs people take besides Actonel? *

  1. Norvasc: 10 people, 27.03%
  2. Sandostatin Lar: 8 people, 21.62%
  3. Symbicort: 6 people, 16.22%
  4. Atenolol: 6 people, 16.22%
  5. Altace: 5 people, 13.51%
  6. Protonix: 5 people, 13.51%
  7. Warfarin Sodium: 5 people, 13.51%
  8. Lasix: 5 people, 13.51%
  9. Hydrochlorothiazide: 5 people, 13.51%
  10. Furosemide: 5 people, 13.51%

What are other side effects people have besides Increased upper airway secretion? *

  1. Cough: 21 people, 56.76%
  2. Weakness: 15 people, 40.54%
  3. Nausea And Vomiting: 15 people, 40.54%
  4. Diarrhea: 12 people, 32.43%
  5. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 11 people, 29.73%
  6. Bone Disorder: 9 people, 24.32%
  7. Dizziness: 9 people, 24.32%
  8. Blood Pressure Systolic Increased: 8 people, 21.62%
  9. Anaemia (lack of blood): 8 people, 21.62%
  10. Ovarian Cysts (fluid filled sacs of the ovary): 8 people, 21.62%

What are the existing conditions these people have? *

  1. Gastric Mucosal Hypertrophy (inflammation and ulcers (breaks on the skin or on the surface of an organ) of the mucosa (inner lining) of the stomach): 8 people, 21.62%
  2. Pain: 4 people, 10.81%
  3. High Blood Pressure: 3 people, 8.11%
  4. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 8.11%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.41%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.41%
  7. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 2 people, 5.41%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.70%
  9. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1 person, 2.70%
  10. Asthma: 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Increased upper airway secretion?

- Check whether Increased upper airway secretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel:

Increased upper airway secretion treatments and more:

How severe was Increased upper airway secretion and when was it recovered:

Expand to all the drugs that have ingredients of risedronate sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Increased upper airway secretion:

Browse all the conditions that are associated with Increased upper airway secretion:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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