Actonel and Ipf - a phase IV clinical study of FDA data

Summary:

Ipf is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Humira, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Ipf when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Ipf?

Ipf is found to be associated with 2,133 drugs and 2,253 conditions by eHealthMe. Check the latest studies of Ipf.

On Jan, 10, 2026

28,929 people reported to have side effects when taking Actonel.
Among them, 328 people (1.13%) have Ipf.

Among these 328 people:

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Ipf?

- Check whether Ipf is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel:

Actonel (29,369 reports)

Ipf treatments and more:

Ipf (79,192 reports)

How severe was Ipf and when was it recovered:

Ipf in Actonel

Expand to all the drugs that have ingredients of risedronate sodium:

Ipf and drugs with ingredients of risedronate sodium (1,115 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Actonel side effects:

Actonel side effect: Fall (2,644 reports)

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Ipf:

Methotrexate side effect: Ipf (4,714 reports)
Prednisone side effect: Ipf (4,117 reports)
Humira side effect: Ipf (2,869 reports)
Enbrel side effect: Ipf (2,842 reports)
Ofev side effect: Ipf (2,063 reports)
Remicade side effect: Ipf (2,043 reports)
Actemra side effect: Ipf (2,024 reports)
Leflunomide side effect: Ipf (1,957 reports)
Xeljanz side effect: Ipf (1,940 reports)
Pantoprazole side effect: Ipf (1,758 reports)

Browse all the drugs that are associated with Ipf:

Ipf (2,128 drugs)

Common conditions associated with Ipf:

Rheumatoid arthritis: 5,843 reports
Ipf: 2,256 reports
Atrial fibrillation: 1,089 reports
Hypertension: 1,023 reports
Htn: 1,015 reports
Psoriatic arthropathy aggravated: 851 reports
Idiopathic pulmonary fibrosis: 843 reports
Primary pulmonary hypertension: 793 reports
Psoriasis aggravated: 789 reports
Osteoporosis: 682 reports

Browse all the conditions that are associated with Ipf:

Ipf (2,253 conditions)

Drugs similar to Actonel and Ipf :

Related publications that referenced our studies

Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.