Actonel and Thrombophlebitis - a phase IV clinical study of FDA data

Summary:

Thrombophlebitis is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Fosamax, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Thrombophlebitis when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Thrombophlebitis?

Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot) is found to be associated with 936 drugs and 1,267 conditions by eHealthMe. Check the latest studies of Thrombophlebitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

28,929 people reported to have side effects when taking Actonel.
Among them, 59 people (0.2%) have Thrombophlebitis.

Among these 59 people:

How long have people been on Actonel when they have Thrombophlebitis? *

What is the gender of people who have Thrombophlebitis when taking Actonel? *

female: 83.02 %
male: 16.98 %

What is the age of people who have Thrombophlebitis when taking Actonel? *

What are other drugs people take besides Actonel? *

What are other side effects people have besides Thrombophlebitis? *

High Blood Pressure: 27 people, 45.76%
Joint Pain: 22 people, 37.29%
Fall: 20 people, 33.90%
Femur Fracture: 19 people, 32.20%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 18 people, 30.51%
Fatigue (feeling of tiredness): 16 people, 27.12%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 15 people, 25.42%
Pain In Extremity: 15 people, 25.42%
Depression: 14 people, 23.73%
Back Pain: 14 people, 23.73%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 18.64%
Polymyalgia Rheumatica (pain in many muscles): 8 people, 13.56%
Hypersensitivity: 7 people, 11.86%
High Blood Cholesterol: 6 people, 10.17%
Asthma: 5 people, 8.47%
High Blood Pressure: 3 people, 5.08%
Pain: 2 people, 3.39%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 3.39%
Ill-Defined Disorder: 2 people, 3.39%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 3.39%

* Approximation only. Some reports may have incomplete information.

Do you take Actonel and have Thrombophlebitis?

- Check whether Thrombophlebitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actonel:

Actonel (29,369 reports)

Thrombophlebitis treatments and more:

Thrombophlebitis (13,501 reports)

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombophlebitis:

Thrombophlebitis (936 drugs)

Browse all the conditions that are associated with Thrombophlebitis:

Thrombophlebitis (1,267 conditions)

Related publications that referenced our studies

Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.