Actonel and Ttp - a phase IV clinical study of FDA data
Summary:
Ttp is reported as a side effect among people who take Actonel (risedronate sodium), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Neoral, and have Hepatitis b.
The phase IV clinical study analyzes which people have Ttp when taking Actonel. It is created by eHealthMe based on reports of 28,929 people who have side effects when taking Actonel from the FDA, and is updated regularly.
What is Actonel?
Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.
What is Ttp?
Ttp is found to be associated with 852 drugs and 827 conditions by eHealthMe. Check the latest studies of Ttp.
28,929 people reported to have side effects when taking Actonel.
Among them, 19 people (0.07%) have Ttp.

Among these 19 people:
How long have people been on Actonel when they have Ttp? *
- < 1 month: 33.33 %
- 1 - 6 months: 11.11 %
- 6 - 12 months: 44.44 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 11.11 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Ttp when taking Actonel? *
- female: 57.89 %
- male: 42.11 %
What is the age of people who have Ttp when taking Actonel? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 14.29 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 14.29 %
- 60+: 71.43 %
What are other drugs people take besides Actonel? *
- Neoral: 7 people, 36.84%
- Lantus: 5 people, 26.32%
- Ramipril: 5 people, 26.32%
- Neurontin: 5 people, 26.32%
- Noxafil: 5 people, 26.32%
- Humalog: 5 people, 26.32%
- Pepcid: 4 people, 21.05%
- Mycophenolic Acid: 3 people, 15.79%
- Zetia: 2 people, 10.53%
- Avapro: 2 people, 10.53%
What are other side effects people have besides Ttp? *
- Septic Shock (shock due to blood infection): 6 people, 31.58%
- Hepatitis Cholestatic (flow of bile from the liver is slowed or blocked): 5 people, 26.32%
- Cytolytic Hepatitis (dissolution or destruction of a liver cell): 5 people, 26.32%
- Escherichia Sepsis (bacterial infection by escherichia coli): 5 people, 26.32%
- Haemoglobin Decreased: 3 people, 15.79%
- High Blood Pressure: 3 people, 15.79%
- Intra-Abdominal Haemorrhage (intra-abdominal bleeding): 3 people, 15.79%
- Gastric Ulcer (stomach ulcer): 2 people, 10.53%
- Dyspnea (difficult or laboured breathing): 2 people, 10.53%
- Calculus Ureteric (stone in ureter): 2 people, 10.53%
What are the existing conditions these people have? *
- Fungal Infection: 5 people, 26.32%
- Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 5 people, 26.32%
- High Blood Pressure: 5 people, 26.32%
- Diabetes: 5 people, 26.32%
- Hepatitis B: 5 people, 26.32%
- Constipation: 3 people, 15.79%
- Lacunar Infarction (a type of stroke): 3 people, 15.79%
- Insomnia (sleeplessness): 3 people, 15.79%
- Nephrogenic Anaemia (anaemia due to kidney disease): 2 people, 10.53%
- Glomerulonephritis Chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli): 2 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Actonel and have Ttp?
- Check whether Ttp is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Actonel:
- Actonel (29,369 reports)
Ttp treatments and more:
- Ttp (6,447 reports)
How severe was Ttp and when was it recovered:
Expand to all the drugs that have ingredients of risedronate sodium:
- Ttp and drugs with ingredients of risedronate sodium (21 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actonel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Ttp:
- Ttp (852 drugs)
Browse all the conditions that are associated with Ttp:
- Ttp (827 conditions)
Related publications that referenced our studies
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on risedronate sodium (the active ingredients of Actonel) and Actonel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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