Actoplus met and Erection problems - a phase IV clinical study of FDA data

Summary:

Erection problems is reported as a side effect among people who take Actoplus met (metformin hydrochloride; pioglitazone hydrochloride), especially for people who are 50-59 old, have been taking the drug for 2 - 5 years also take Janumet, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Erection problems when taking Actoplus met. It is created by eHealthMe based on reports of 1,111 people who have side effects when taking Actoplus met from the FDA, and is updated regularly.

What is Actoplus met?

Actoplus met has active ingredients of metformin hydrochloride; pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 1,210 Actoplus met users. Check the latest studies of Actoplus met.

What is Erection problems?

Erection problems is found to be associated with 1,272 drugs and 2,037 conditions by eHealthMe. Check the latest studies of Erection problems.

On Apr, 14, 2026

1,111 people reported to have side effects when taking Actoplus met.
Among them, 15 people (1.35%) have Erection problems.

Could Actoplus met cause Erection problems?

Among these 15 people:

How long have people been on Actoplus met when they have Erection problems? *

What is the age of people who have Erection problems when taking Actoplus met? *

What are other drugs people take besides Actoplus met? *

What are other side effects people have besides Erection problems? *

Weakness: 6 people, 40.00%
Anaemia (lack of blood): 5 people, 33.33%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 5 people, 33.33%
Abdominal Pain: 4 people, 26.67%
Urinary Tract Infection: 4 people, 26.67%
Hypotension (abnormally low blood pressure): 4 people, 26.67%
Diarrhea: 4 people, 26.67%
Hyperhidrosis (abnormally increased sweating): 4 people, 26.67%
Memory Loss: 4 people, 26.67%
Hearing Loss: 3 people, 20.00%

What are the existing conditions these people have? *

Pain: 4 people, 26.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 26.67%
Stress And Anxiety: 3 people, 20.00%
Indigestion: 3 people, 20.00%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 3 people, 20.00%
Depression: 3 people, 20.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 20.00%
Chest Pain: 3 people, 20.00%
Muscle Aches (muscle pain): 2 people, 13.33%
Hypersensitivity: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Actoplus met and have Erection problems?

- Check whether Erection problems is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actoplus met:

Actoplus met (1,210 reports)

Erection problems treatments and more:

Erection problems (80,352 reports)

How severe was Erection problems and when was it recovered:

Erection problems in Actoplus met

Expand to all the drugs that have ingredients of metformin hydrochloride; pioglitazone hydrochloride:

Erection problems and drugs with ingredients of metformin hydrochloride; pioglitazone hydrochloride (15 reports)

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actoplus met:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Erection problems:

Erection problems (1,272 drugs)

Browse all the conditions that are associated with Erection problems:

Erection problems (2,037 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride; pioglitazone hydrochloride (the active ingredients of Actoplus met) and Actoplus met (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.