Actos and Hostility - a phase IV clinical study of FDA data

Summary:

Hostility is reported as a side effect among people who take Actos (pioglitazone hydrochloride), especially for people who are male, 60+ old, also take Lipitor, and have Gastric disorder.

The phase IV clinical study analyzes which people have Hostility when taking Actos. It is created by eHealthMe based on reports of 49,087 people who have side effects when taking Actos from the FDA, and is updated regularly.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

What is Hostility?

Hostility is found to be associated with 403 drugs and 420 conditions by eHealthMe. Check the latest studies of Hostility.

On Jan, 19, 2026

49,087 people reported to have side effects when taking Actos.
Among them, 14 people (0.03%) have Hostility.

Among these 14 people:

What is the gender of people who have Hostility when taking Actos? *

female: 14.29 %
male: 85.71 %

What is the age of people who have Hostility when taking Actos? *

What are other drugs people take besides Actos? *

What are other side effects people have besides Hostility? *

Agitation (state of anxiety or nervous excitement): 8 people, 57.14%
Suicidal Ideation: 4 people, 28.57%
Speech Disorder: 3 people, 21.43%
Memory Loss: 3 people, 21.43%
Mood Swings (an extreme or rapid change in mood): 3 people, 21.43%
Bedridden: 3 people, 21.43%
Pharyngeal Oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 3 people, 21.43%
Depressed Mood: 3 people, 21.43%
Hypokinesia (decreased bodily movement): 3 people, 21.43%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 21.43%

What are the existing conditions these people have? *

Quit Smoking: 3 people, 21.43%
Neuropathy Peripheral (surface nerve damage): 3 people, 21.43%
High Blood Pressure: 3 people, 21.43%
High Blood Cholesterol: 3 people, 21.43%
Gastric Disorder (disease of stomach): 3 people, 21.43%
Depression: 2 people, 14.29%
Joint Pain: 1 person, 7.14%
Bipolar Disorder (mood disorder): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Actos and have Hostility?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actos:

Actos (49,754 reports)

Hostility treatments and more:

Hostility (4,283 reports)

Browse all side effects of Actos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hostility:

Hostility (403 drugs)

Browse all the conditions that are associated with Hostility:

Hostility (420 conditions)

Drugs similar to Actos and Hostility :

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride (the active ingredients of Actos) and Actos (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.