Actos and Prostatic specific antigen increased - a phase IV clinical study of FDA data

Summary:

Prostatic specific antigen increased is reported as a side effect among people who take Actos (pioglitazone hydrochloride), especially for people who are 60+ old, have been taking the drug for 5 - 10 years also take Januvia, and have Prostate cancer.

The phase IV clinical study analyzes which people have Prostatic specific antigen increased when taking Actos. It is created by eHealthMe based on reports of 49,087 people who have side effects when taking Actos from the FDA, and is updated regularly.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

What is Prostatic specific antigen increased?

Prostatic specific antigen increased is found to be associated with 717 drugs and 692 conditions by eHealthMe. Check the latest studies of Prostatic specific antigen increased.

On Aug, 04, 2026

49,087 people reported to have side effects when taking Actos.
Among them, 31 people (0.06%) have Prostatic specific antigen increased.

Could Actos cause Prostatic specific antigen increased?

Among these 31 people:

How long have people been on Actos when they have Prostatic specific antigen increased? *

What is the age of people who have Prostatic specific antigen increased when taking Actos? *

What are other drugs people take besides Actos? *

Januvia: 8 people, 25.81%
Crestor: 6 people, 19.35%
Metformin: 6 people, 19.35%
Aspirin: 4 people, 12.90%
Revlimid: 4 people, 12.90%
Furosemide: 4 people, 12.90%
Byetta: 4 people, 12.90%
Benazepril Hydrochloride: 3 people, 9.68%
Glucotrol: 3 people, 9.68%
Atacand: 3 people, 9.68%

What are other side effects people have besides Prostatic specific antigen increased? *

Blood Glucose Increased: 6 people, 19.35%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 6 people, 19.35%
Bladder Cancer: 4 people, 12.90%
Pain: 4 people, 12.90%
Urinary Tract Infection: 4 people, 12.90%
Drug Ineffective: 3 people, 9.68%
Gallbladder Disorder: 3 people, 9.68%
General Physical Health Deterioration (weak health status): 3 people, 9.68%
Weight Decreased: 3 people, 9.68%
Glycosylated Haemoglobin Increased: 3 people, 9.68%

What are the existing conditions these people have? *

Prostate Cancer: 5 people, 16.13%
Heart Rate Irregular: 3 people, 9.68%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 3.23%
Pain: 1 person, 3.23%
Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 3.23%
Multiple Myeloma (cancer of the plasma cells): 1 person, 3.23%
Mitral Valve Incompetence (inefficient heart valve): 1 person, 3.23%
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 1 person, 3.23%
Dyspnea (difficult or laboured breathing): 1 person, 3.23%
Depression: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Actos and have Prostatic specific antigen increased?

- Check whether Prostatic specific antigen increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Actos:

Actos (49,754 reports)

Browse all side effects of Actos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Prostatic specific antigen increased:

Prostatic specific antigen increased (717 drugs)

Browse all the conditions that are associated with Prostatic specific antigen increased:

Prostatic specific antigen increased (692 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride (the active ingredients of Actos) and Actos (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.